Procarbazine hydrochloride cas no:366-70-1
Synonyms: Benzamide,N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]-, monohydrochloride (9CI);p-Toluamide, N-isopropyl-a-(2-methylhydrazino)-, monohydrochloride (8CI);1-Methyl-2-[p-(isopropylcarbamoyl)benzyl]hydrazine hydrochloride;2-[p-(Isopropylcarbamoyl)benzyl]-1-methylhydrazine hydrochloride;IBZ;Ibenzmethyzin hydrochloride;Ibenzmethyzine hydrochloride;MBH;MIHhydrochloride;Matulane;N-Isopropyl-p-(2-methylhydrazinomethyl)benzamidehydrochloride;N-Isopropyl-a-(2-methylhydrazino)-p-toluamide hydrochloride;NCI-C 01810;NSC 77213;Nathulane;Natulan;Natulan hydrochloride;Natulanar;PCB hydrochloride;Ro 4 6467/1;Ro 4-6467;Benzamide,N-(1-methylethyl)-4-[(2-methylhydrazinyl)methyl]-, hydrochloride (1:1);
NameProcarbazine hydrochloride
CAS366-70-1
SynonymsBenzamide,N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]-, monohydrochloride (9CI);p-Toluamide, N-isopropyl-a-(2-methylhydrazino)-, monohydrochloride (8CI);1-Methyl-2-[p-(isopropylcarbamoyl)benzyl]hydrazine hydrochloride;2-[p-(Isopropylcarbamoyl)benzyl]-1-methylhydrazine hydrochloride;IBZ;Ibenzmethyzin hydrochloride;Ibenzmethyzine hydrochloride;MBH;MIHhydrochloride;Matulane;N-Isopropyl-p-(2-methylhydrazinomethyl)benzamidehydrochloride;N-Isopropyl-a-(2-methylhydrazino)-p-toluamide hydrochloride;NCI-C 01810;NSC 77213;Nathulane;Natulan;Natulan hydrochloride;Natulanar;PCB hydrochloride;Ro 4 6467/1;Ro 4-6467;Benzamide,N-(1-methylethyl)-4-[(2-methylhydrazinyl)methyl]-, hydrochloride (1:1);
EINECS(EC#)206-678-6
Molecular FormulaC12H19N3O.HCl
Molecular Weight257.80
Appearancewhite to pale yellow crystalline powder
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Safety
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by an unspecified route. Moderately toxic by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used as a chemotherapeutic agent.
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dnd-rat-ipr 25 mg/kg
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hma-mus/esc 100 mg/kg
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orl-rat LD50:570 mg/kg
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scu-rat LD50:490 mg/kg
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ivn-rat LD50:350 mg/kg
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orl-rat LD50:785 mg/kg
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orl-mus LD50:560 mg/kg
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ipr-mus LD50:699 mg/kg
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scu-mus LD50:710 mg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),467. |
