2H-1,4-Benzodiazepine-2-thione,7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)- cas no:36735-22-5
Synonyms: 7-Chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-2-thione;7-Chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(o-fluorophenyl)-2H-1,4-benzodiazepine-2-thione;Doral; Dormalin; NSC 309702; Oniria; Prosedar; Quazepam; Quazium; Sch 16134;Selepam
Name2H-1,4-Benzodiazepine-2-thione,7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-
CAS36735-22-5
Synonyms7-Chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-2-thione;7-Chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-(o-fluorophenyl)-2H-1,4-benzodiazepine-2-thione;Doral; Dormalin; NSC 309702; Oniria; Prosedar; Quazepam; Quazium; Sch 16134;Selepam
EINECS(EC#)253-179-4
Molecular FormulaC17H11 Cl F4 N2 S
Molecular Weight386.7943
refractive index1.595
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety
Safety information of 2H-1,4-Benzodiazepine-2-thione, 7-chloro-5- (2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)- (36735-22-5):
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| cat |
LD |
oral |
> 1gm/kg (1000mg/kg) |
BEHAVIORAL: ATAXIA
BEHAVIORAL: ANALGESIA |
Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 1456, 1982. |
| dog |
LD |
oral |
> 1gm/kg (1000mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 37, Pg. 906, 1987. |
| mouse |
LD50 |
intraperitoneal |
845mg/kg (845mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Arzneimittel-Forschung. Drug Research. Vol. 37, Pg. 906, 1987. |
| mouse |
LDLo |
oral |
5gm/kg (5000mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 1456, 1982. |
| rat |
LD50 |
intraperitoneal |
2749mg/kg (2749mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Arzneimittel-Forschung. Drug Research. Vol. 37, Pg. 906, 1987. |
| rat |
LD50 |
oral |
> 5gm/kg (5000mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 37, Pg. 906, 1987. |
