Benzene,1-chloro-4-(isothiocyanatomethyl)- cas no:3694-45-9

NameBenzene,1-chloro-4-(isothiocyanatomethyl)-
CAS3694-45-9
SynonymsIsothiocyanicacid, p-chlorobenzyl ester (7CI,8CI); Toluene, p-chloro-a-isothiocyanato- (6CI);1-Chloro-4-(isothiocyanatomethyl)benzene;1-Isothiocyanatomethyl-4-chlorobenzene; 4-Chlorobenzyl isothiocyanate; NSC221238; p-Chlorobenzyl isothiocyanate
Molecular FormulaC8H6 Cl N S
Molecular Weight183.65

refractive index1.6155
Sensitive Moisture Sensitive

Hazardclass6.1

Hazard T: Toxic;
Risk R20/21/22;R36/37/38
Safety

Hazard Codes: T
Risk Statements: 20/21/22-36/37/38
R20/21/22: 4-Chlorobenzyl isothiocyanate (CAS NO.3694-45-9) is harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
RIDADR: 2810
RTECS: NX8470000
HazardClass: 6.1
PackingGroup: II

Poison by intraperitoneal and intravenous routes. See also ESTERS and THIOCYANATES. When 4-Chlorobenzyl isothiocyanate (CAS NO.3694-45-9) is heated to decomposition, it emits very toxic fumes of SO_x, Cl⁻ and CN⁻.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	56mg/kg (56mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02757,
mouse	LDLo	intraperitoneal	100mg/kg (100mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 121, 1971.
rat	LDLo	intraperitoneal	100mg/kg (100mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 870, 1966.