L-Proline,1-[[[[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenyl]carbonyl]amino]methyl]- cas no:37106-99-3

NameL-Proline,1-[[[[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenyl]carbonyl]amino]methyl]-
CAS37106-99-3
SynonymsL-Proline,1-[[[[4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenyl]carbonyl]amino]methyl]-,[4S-(4a,4aa,5aa,6b,12aa)]-; Prolinomethyltetracycline
Molecular FormulaC28H33 N3 O10
Molecular Weight571.64

refractive index1.726

Safety

Poison by intramuscular, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of NO_x.

1.		ipr-rat LD50:115 mg/kg		JJANAX    Japanese Journal of Antibiotics. 25 (1972),95.
2.		scu-rat LD50:1733 mg/kg		KSRNAM    Kiso to Rinsho. Clinical Report. 6 (1972),51.
3.		ivn-rat LD50:144 mg/kg		KSRNAM    Kiso to Rinsho. Clinical Report. 6 (1972),51.
4.		ims-rat LD50:788 mg/kg		KSRNAM    Kiso to Rinsho. Clinical Report. 6 (1972),51.
5.		ipr-mus LD50:353 mg/kg		KSRNAM    Kiso to Rinsho. Clinical Report. 6 (1972),51.
6.		scu-mus LD50:1465 mg/kg		KSRNAM    Kiso to Rinsho. Clinical Report. 6 (1972),51.
7.		ivn-mus LD50:85,100 µg/kg		KSRNAM    Kiso to Rinsho. Clinical Report. 6 (1972),51.
8.		ims-mus LD50:283 mg/kg		JJANAX    Japanese Journal of Antibiotics. 24 (1971),156.