372-09-8|Cyanoacetic acidProducts Supply - Chemical intermediates Network

Cyanoacetic acid cas no:372-09-8

Synonyms: Methyl and Ethyl esters;

Identification

NameCyanoacetic acid
CAS372-09-8
SynonymsMethyl and Ethyl esters;
EINECS(EC#)206-743-9
Molecular FormulaC3H3NO2
Molecular Weight85.06

Chemical Properties

Appearanceyellow-brown liquid with an unpleasant odor
storage tempStore at 0-5°C
Sensitive Hygroscopic

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass8

Safety Data

Hazard C:Corrosive
Risk R20/22;R31;R34;R52/53
Safety

Hazard Codes:? Corrosive C
Risk Statements: 22-31-34-52/53-20/22?
R22:Harmful if swallowed.?
R31 :Contact with acids liberates toxic gas.?
R34:Causes burns.?
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R20/22:Harmful by inhalation and if swallowed.
Safety Statements: 26-36/37/39-45-61-20?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.?
S20:When using, do not eat or drink.
RIDADR: UN 3261 8/PG 2
WGK Germany: 2
RTECS: AG3675000
F: 3-10-21
HazardClass: 8
PackingGroup: II

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
frog	LDLo	subcutaneous	1300mg/kg (1300mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899.
mouse	LD50	intraperitoneal	200mg/kg (200mg/kg)	?	National Technical Information Service. Vol. AD691-490,
rabbit	LDLo	subcutaneous	1900mg/kg (1900mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899.
rat	LD50	oral	1500mg/kg (1500mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Personal Communication from LONZA Ltd., CH-4002, Basel, SwitzerlandVol. 12JAN1981,

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Cyanoacetic acid cas no:372-09-8

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