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Cyanoacetic acid cas no:372-09-8

Synonyms: Methyl and Ethyl esters;

Identification
NameCyanoacetic acid
CAS372-09-8
SynonymsMethyl and Ethyl esters;
EINECS(EC#)206-743-9
Molecular FormulaC3H3NO2
Molecular Weight85.06
Chemical Properties
Appearanceyellow-brown liquid with an unpleasant odor
storage tempStore at 0-5°C
Sensitive Hygroscopic
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass8
Safety Data

Hazard C:Corrosive
Risk R20/22;R31;R34;R52/53
Safety

Hazard Codes:?CorrosiveC
Risk Statements: 22-31-34-52/53-20/22?
R22:Harmful if swallowed.?
R31 :Contact with acids liberates toxic gas.?
R34:Causes burns.?
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R20/22:Harmful by inhalation and if swallowed.
Safety Statements: 26-36/37/39-45-61-20?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.?
S20:When using, do not eat or drink.
RIDADR: UN 3261 8/PG 2
WGK Germany: 2
RTECS: AG3675000
F: 3-10-21
HazardClass: 8
PackingGroup: II


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo subcutaneous 1300mg/kg (1300mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899.
mouse LD50 intraperitoneal 200mg/kg (200mg/kg) ? National Technical Information Service. Vol. AD691-490,
rabbit LDLo subcutaneous 1900mg/kg (1900mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899.
rat LD50 oral 1500mg/kg (1500mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Personal Communication from LONZA Ltd., CH-4002, Basel, SwitzerlandVol. 12JAN1981,

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