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Detralfate (9CI) cas no:37209-31-7

Synonyms: Detralfate

Identification
NameDetralfate (9CI)
CAS37209-31-7
SynonymsDetralfate
Molecular FormulaC12H22O25S5
Molecular Weight0
Chemical Properties
refractive index1.685
Safety Data

Safety

Poison by intraperitoneal route. Moderately toxic by subcutaneous route. Used as an antipeptic ulcer agent. When Detralfate (CAS NO.37209-31-7) is heated to decomposition ,it emits toxic fumes of SOx and Na2O. See also DEXTRAN SULFATE SODIUM.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 257mg/kg (257mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 3, Pg. 24, 1972.
mouse LD50 oral > 4gm/kg (4000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 3, Pg. 24, 1972.
mouse LD50 subcutaneous 2200mg/kg (2200mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 3, Pg. 24, 1972.
rat LD50 intraperitoneal 200mg/kg (200mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 3, Pg. 24, 1972.
rat LD50 oral > 6400mg/kg (6400mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 3, Pg. 24, 1972.
rat LD50 subcutaneous 1600mg/kg (1600mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 3, Pg. 24, 1972.

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