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Phosphorothioic acid,O,O-dimethyl O-[3-methyl-4-(methylsulfinyl)phenyl] ester cas no:3761-41-9

Synonyms: Phosphorothioicacid, O,O-dimethyl O-[4-(methylsulfinyl)-m-tolyl] ester (7CI,8CI);Fensulfoxide; Fenthion sulfoxide; Mesulfenfos; Mesulfenphos

Identification
NamePhosphorothioic acid,O,O-dimethyl O-[3-methyl-4-(methylsulfinyl)phenyl] ester
CAS3761-41-9
SynonymsPhosphorothioicacid, O,O-dimethyl O-[4-(methylsulfinyl)-m-tolyl] ester (7CI,8CI);Fensulfoxide; Fenthion sulfoxide; Mesulfenfos; Mesulfenphos
EINECS(EC#)200-835-2
Molecular FormulaC10H15 O4 P S2
Molecular Weight294.34
Chemical Properties
refractive index1.584
storage tempAPPROX 4°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard F,Xn,N,T
Risk 11-20/21/22-36-50/53-25
Safety

Hazard Codes: FlammableF,HarmfulXn,DangerousN,ToxicT
Risk Statements: 11-20/21/22-36-50/53-25
R11: Highly flammable. 
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed. 
R25 : Toxic if swallowed. 
R36: O,O-Dimethyl O-(4-(methylsulfinyl)-m-tolyl) phosphorothioate (CAS NO.3761-41-9) can be irritating to eyes. 
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 16-26-36-60-61-45
S16: Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36: Wear suitable protective clothing. 
S60: This material and its container must be disposed of as hazardous waste. 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: 2783
RTECS: TF9400000
HazardClass: 6.1(b)
PackingGroup III
Poison by ingestion and intraperitoneal routes. When O,O-Dimethyl O-(4-(methylsulfinyl)-m-tolyl) phosphorothioate (CAS NO.3761-41-9) is heated to decomposition, it emits very toxic fumes of POx and SOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intracrebral 5mg/kg (5mg/kg)   Pesticide Biochemistry and Physiology. Vol. 8, Pg. 302, 1978.
mouse LD50 oral 220mg/kg (220mg/kg) BEHAVIORAL: TREMOR

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Journal of Pharmacobio-Dynamics. Vol. 9, Pg. 697, 1986.
rat LD50 intraperitoneal 250mg/kg (250mg/kg)   Toxicology and Applied Pharmacology. Vol. 6, Pg. 86, 1964.
rat LD50 oral 125mg/kg (125mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 279, 1973.
rat LDLo skin 3gm/kg (3000mg/kg) PERIPHERAL NERVE AND SENSATION: FASCICULATIONS Bulletin of the World Health Organization. Vol. 29, Pg. 205, 1963.

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