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Hazard T: Toxic;N: Dangerous for the environment;
Risk 25-50/53
Safety
Hazard Codes:
T,
N
Risk Statements: 25-50/53
R25 : Toxic if swallowed.
R50/53: O,O-Dimethyl O-(4-(methylsulfonyl)-m-tolyl) phosphorothioate (CAS NO.3761-42-0) is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 45-60-61
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60: This material and its container must be disposed of as hazardous waste.
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 2783
RTECS: TF9420000
HazardClass: 6.1(b)
PackingGroup: III
Poison by ingestion and intraperitoneal routes. When O,O-Dimethyl O-(4-(methylsulfonyl)-m-tolyl) phosphorothioate (CAS NO.3761-42-0) is heated to decomposition ,it emits very toxic fumes of POx and SOx.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intracrebral | 25mg/kg (25mg/kg) | Pesticide Biochemistry and Physiology. Vol. 8, Pg. 302, 1978. | |
| mouse | LD50 | oral | 210mg/kg (210mg/kg) | BEHAVIORAL: TREMOR GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS |
Journal of Pharmacobio-Dynamics. Vol. 9, Pg. 697, 1986. |
| rat | LD50 | intraperitoneal | 250mg/kg (250mg/kg) | Toxicology and Applied Pharmacology. Vol. 6, Pg. 86, 1964. | |
| rat | LD50 | oral | 125mg/kg (125mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 279, 1973. | |
| rat | LDLo | skin | 1600mg/kg (1600mg/kg) | PERIPHERAL NERVE AND SENSATION: FASCICULATIONS | Bulletin of the World Health Organization. Vol. 29, Pg. 205, 1963. |
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