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Phosphorothioic acid,O,O-dimethyl O-[3-methyl-4-(methylsulfonyl)phenyl] ester cas no:3761-42-0

Synonyms: Phosphorothioicacid, O,O-dimethyl O-[4-(methylsulfonyl)-m-tolyl] ester (7CI,8CI);Fenthionsulfone

Identification
NamePhosphorothioic acid,O,O-dimethyl O-[3-methyl-4-(methylsulfonyl)phenyl] ester
CAS3761-42-0
SynonymsPhosphorothioicacid, O,O-dimethyl O-[4-(methylsulfonyl)-m-tolyl] ester (7CI,8CI);Fenthionsulfone
Molecular FormulaC10H15 O5 P S2
Molecular Weight310.34
Chemical Properties
refractive index1.54
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T: Toxic;N: Dangerous for the environment;
Risk 25-50/53
Safety

Hazard Codes: ToxicT,DangerousN
Risk Statements: 25-50/53
R25 : Toxic if swallowed. 
R50/53: O,O-Dimethyl O-(4-(methylsulfonyl)-m-tolyl) phosphorothioate (CAS NO.3761-42-0) is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 45-60-61
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S60: This material and its container must be disposed of as hazardous waste. 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 2783
RTECS: TF9420000
HazardClass: 6.1(b)
PackingGroup: III
Poison by ingestion and intraperitoneal routes. When O,O-Dimethyl O-(4-(methylsulfonyl)-m-tolyl) phosphorothioate (CAS NO.3761-42-0) is heated to decomposition ,it emits very toxic fumes of POx and SOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intracrebral 25mg/kg (25mg/kg)   Pesticide Biochemistry and Physiology. Vol. 8, Pg. 302, 1978.
mouse LD50 oral 210mg/kg (210mg/kg) BEHAVIORAL: TREMOR

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Journal of Pharmacobio-Dynamics. Vol. 9, Pg. 697, 1986.
rat LD50 intraperitoneal 250mg/kg (250mg/kg)   Toxicology and Applied Pharmacology. Vol. 6, Pg. 86, 1964.
rat LD50 oral 125mg/kg (125mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 279, 1973.
rat LDLo skin 1600mg/kg (1600mg/kg) PERIPHERAL NERVE AND SENSATION: FASCICULATIONS Bulletin of the World Health Organization. Vol. 29, Pg. 205, 1963.

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