Ethanol,2-[[3-(2-chloroethyl)tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-2-yl]amino]-,1-methanesulfonate cas no:37753-10-9

Synonyms: Ethanol,2-[[3-(2-chloroethyl)tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-2-yl]amino]-,methanesulfonate (ester) (9CI); Ethanol,2-[[3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-yl]amino]-,methanesulfonate (ester), P-oxide; 2H-1,3,2-Oxazaphosphorine, ethanol deriv.;Asta 5122; Sufosfamide

Identification

NameEthanol,2-[[3-(2-chloroethyl)tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-2-yl]amino]-,1-methanesulfonate
CAS37753-10-9
SynonymsEthanol,2-[[3-(2-chloroethyl)tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-2-yl]amino]-,methanesulfonate (ester) (9CI); Ethanol,2-[[3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-yl]amino]-,methanesulfonate (ester), P-oxide; 2H-1,3,2-Oxazaphosphorine, ethanol deriv.;Asta 5122; Sufosfamide
Molecular FormulaC8H18 Cl N2 O5 P S
Molecular Weight320.76

Chemical Properties

refractive index1.516

Safety Data

Safety

Poison by intravenous and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits very toxic fumes of PO_x, SO_x, Cl⁻, and NO_x.

Toxicity

1.	mnt-mus-ipr 160 mg/kg/24H	MUREAV Mutation Research. 56 (1978),319.
2.	ipr-rat LD50:120 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 24 (1974),1149.
3.	ivn-rat LD50:102 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 24 (1974),1149.
4.	ipr-mus LD50:136 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 24 (1974),1149.
5.	ivn-mus LD50:91 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 24 (1974),1149.

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