Propyperone cas no:3781-28-0

Synonyms: Butyrophenone,4'-fluoro-4-(4-piperidino-4-propionylpiperidino)- (7CI,8CI); 4'-Fluoro-4-(4-piperidino-4-propionylpiperidino)butyrophenone;Floropipeton

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Identification
Chemical Properties
Safety Data
Toxicity

Identification

NamePropyperone
CAS3781-28-0
SynonymsButyrophenone,4'-fluoro-4-(4-piperidino-4-propionylpiperidino)- (7CI,8CI); 4'-Fluoro-4-(4-piperidino-4-propionylpiperidino)butyrophenone;Floropipeton
Molecular FormulaC23H33 F N2 O2
Molecular Weight388.58

Chemical Properties

refractive index1.534

Safety Data

Safety

Poison by ingestion and subcutaneous routes. When heated to decomposition Propyperone (CAS NO.3781-28-0) emits very toxic fumes of F⁻ and NO_x.

Toxicity

1.	orl-rat LD50:780 mg/kg	27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,192.
2.	scu-rat LD50:350 mg/kg	27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,192.
3.	orl-mus LD50:275 mg/kg	27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,192.
4.	scu-mus LD50:420 mg/kg	27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,192.

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