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Pirbuterol hydrochloride cas no:38029-10-6

Synonyms: alpha6-[[(tert-butyl)amino]methyl]-3-hydroxypyridine-2,6-dimethanol dihydrochloride;Pirbuterol dihydrochloride;Pyrbuterol hydrochloride

Identification
NamePirbuterol hydrochloride
CAS38029-10-6
Synonymsalpha6-[[(tert-butyl)amino]methyl]-3-hydroxypyridine-2,6-dimethanol dihydrochloride;Pirbuterol dihydrochloride;Pyrbuterol hydrochloride
EINECS(EC#)253-751-3
Molecular FormulaC12H20N2O3 . 2ClH
Molecular Weight313.22068
Safety Data

Safety

Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits NOx and HCl.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 42mg/kg (42mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 637, 1982.
mouse LD50 oral 2gm/kg (2000mg/kg)   Medicamentos de Actualidad. Vol. 19, Pg. 382, 1983.
mouse LD50 subcutaneous 280mg/kg (280mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 637, 1982.
rat LD50 intravenous 53mg/kg (53mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 637, 1982.
rat LD50 oral 2gm/kg (2000mg/kg)   Medicamentos de Actualidad. Vol. 19, Pg. 382, 1983.
rat LD50 subcutaneous 645mg/kg (645mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 689, 1980.

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