3810-74-0|D-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?2)-O-5-deoxy-3-C-formyl-a-L-lyxofuranosyl-(1?4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3)Products Supply

D-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?2)-O-5-deoxy-3-C-formyl-a-L-lyxofuranosyl-(1?4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3) cas no:3810-74-0

Synonyms: D-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?;4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)(9CI);Streptomycin, sulfate (2:3) (salt) (8CI);Ag Streptomycin;Agri-Strep;Agrimycin 17;Agrimycin sulfate;Ambistryn S;Hortocyna;KeyStrepto;Strepto;Streptobrettin;Streptomycinsesquisulfate;Streptomycin sesquisulphate;Streptonex;Strycin;

Identification

NameD-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?2)-O-5-deoxy-3-C-formyl-a-L-lyxofuranosyl-(1?4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3)
CAS3810-74-0
SynonymsD-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?;4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)(9CI);Streptomycin, sulfate (2:3) (salt) (8CI);Ag Streptomycin;Agri-Strep;Agrimycin 17;Agrimycin sulfate;Ambistryn S;Hortocyna;KeyStrepto;Strepto;Streptobrettin;Streptomycinsesquisulfate;Streptomycin sesquisulphate;Streptonex;Strycin;
EINECS(EC#)223-286-0
Molecular FormulaC₄₂H₈₄N₁₄O₃₆S₃
Molecular Weight1457.38

Chemical Properties

AppearanceWhite to off-white powder
refractive index-85 ° (C=1, H2O)
storage temp2-8°C

Safety Data

Hazard Xn:Harmful
Risk R22
Safety

Moderately toxic by ingestion and subcutaneous routes. Human teratogenic effects by intramuscular route: developmental abnormalities of the eye and ear. When heated to decomposition it emits very toxic fumes of SO_x and NO_x. See also STREPTOMYCIN and SULFATES.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
hamster	LD50	oral	400mg/kg (400mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: FOOD INTAKE (ANIMAL) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Toxicology and Applied Pharmacology. Vol. 14, Pg. 510, 1969.
infant	TDLo	intraperitoneal	170mg/kg (170mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	British Medical Journal. Vol. 1, Pg. 557, 1961.
mouse	LD50	intravenous	90200ug/kg (90.2mg/kg)	?	Antibiotiki. Vol. 18, Pg. 444, 1973.
mouse	LD50	oral	430mg/kg (430mg/kg)	?	"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 106, 1982.
mouse	LD50	subcutaneous	403mg/kg (403mg/kg)	?	Antibiotics Annual. Vol. 4, Pg. 574, 1956/1957.
rat	LD50	oral	430mg/kg (430mg/kg)	?	"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 106, 1982.
rat	LD50	subcutaneous	600mg/kg (600mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 597, 1962.

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D-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?2)-O-5-deoxy-3-C-formyl-a-L-lyxofuranosyl-(1?4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3) cas no:3810-74-0

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