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Home > products > D-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?2)-O-5-deoxy-3-C-formyl-a-L-lyxofuranosyl-(1?4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3)

D-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?2)-O-5-deoxy-3-C-formyl-a-L-lyxofuranosyl-(1?4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3) cas no:3810-74-0

Synonyms: D-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?;4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)(9CI);Streptomycin, sulfate (2:3) (salt) (8CI);Ag Streptomycin;Agri-Strep;Agrimycin 17;Agrimycin sulfate;Ambistryn S;Hortocyna;KeyStrepto;Strepto;Streptobrettin;Streptomycinsesquisulfate;Streptomycin sesquisulphate;Streptonex;Strycin;

Identification
NameD-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?2)-O-5-deoxy-3-C-formyl-a-L-lyxofuranosyl-(1?4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3)
CAS3810-74-0
SynonymsD-Streptamine,O-2-deoxy-2-(methylamino)-a-L-glucopyranosyl-(1?;4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)(9CI);Streptomycin, sulfate (2:3) (salt) (8CI);Ag Streptomycin;Agri-Strep;Agrimycin 17;Agrimycin sulfate;Ambistryn S;Hortocyna;KeyStrepto;Strepto;Streptobrettin;Streptomycinsesquisulfate;Streptomycin sesquisulphate;Streptonex;Strycin;
EINECS(EC#)223-286-0
Molecular FormulaC42H84N14O36S3
Molecular Weight1457.38
Chemical Properties
AppearanceWhite to off-white powder
refractive index-85 ° (C=1, H2O)
storage temp2-8°C
Safety Data

Hazard Xn:Harmful
Risk R22
Safety

Moderately toxic by ingestion and subcutaneous routes. Human teratogenic effects by intramuscular route: developmental abnormalities of the eye and ear. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also STREPTOMYCIN and SULFATES.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
hamster LD50 oral 400mg/kg (400mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: FOOD INTAKE (ANIMAL)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Toxicology and Applied Pharmacology. Vol. 14, Pg. 510, 1969.
infant TDLo intraperitoneal 170mg/kg (170mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
British Medical Journal. Vol. 1, Pg. 557, 1961.
mouse LD50 intravenous 90200ug/kg (90.2mg/kg) ? Antibiotiki. Vol. 18, Pg. 444, 1973.
mouse LD50 oral 430mg/kg (430mg/kg) ? "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 106, 1982.
mouse LD50 subcutaneous 403mg/kg (403mg/kg) ? Antibiotics Annual. Vol. 4, Pg. 574, 1956/1957.
rat LD50 oral 430mg/kg (430mg/kg) ? "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 106, 1982.
rat LD50 subcutaneous 600mg/kg (600mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 597, 1962.

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