4-Piperidinecarboxylicacid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride(1:1) cas no:3810-80-8
Synonyms: 4-Piperidinecarboxylicacid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, monohydrochloride(9CI); Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethylester, hydrochloride (6CI,7CI); Isonipecotic acid,1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, monohydrochloride (8CI);1-(3-Cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid ethyl esterhydrochloride; 2,2-Diphenyl-4-(4-carbethoxy-4-phenyl-1-piperidino)butyronitrilehydrochloride; 2,2-Diphenyl-4-(4-carboxy-4-phenyl-1-piperidino)butyronitrileethyl ester hydrochloride; Diphenoxylate hydrochloride; R 1132; R 1132(antiperistaltic)
Name4-Piperidinecarboxylicacid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride(1:1)
CAS3810-80-8
Synonyms4-Piperidinecarboxylicacid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, monohydrochloride(9CI); Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethylester, hydrochloride (6CI,7CI); Isonipecotic acid,1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, monohydrochloride (8CI);1-(3-Cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid ethyl esterhydrochloride; 2,2-Diphenyl-4-(4-carbethoxy-4-phenyl-1-piperidino)butyronitrilehydrochloride; 2,2-Diphenyl-4-(4-carboxy-4-phenyl-1-piperidino)butyronitrileethyl ester hydrochloride; Diphenoxylate hydrochloride; R 1132; R 1132(antiperistaltic)
EINECS(EC#)223-287-6
Molecular FormulaC30H32 N2 O2 . Cl H
Molecular Weight489.10
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety
A poison by ingestion. When heated to decomposition it emits very toxic fumes of HCl and NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
> 320mg/kg (320mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1636, 1974. |
| mouse |
LD50 |
subcutaneous |
> 160mg/kg (160mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1636, 1974. |
| rat |
LD50 |
oral |
221mg/kg (221mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1633, 1974. |
