PENBUTOLOL SULFATE cas no:38363-32-5

NamePENBUTOLOL SULFATE
CAS38363-32-5
Synonyms(-)-1-(tert-butylamino)-3-(o-cyclopentylphenoxyl)-2-propanolsulfate;(-)-terbuclomine;(s)-1-(2-cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)-2-propanolsulfate;1-(2-cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)-2-propano(s)-2-propanosulfa;penbutololsulfate;penbutololsulfato;PENBUTOLOL SULFATE (200 MG);(S)-bis[di-tert-butyl[3-(2-cyclopentylphenoxy)-2-hydroxypropyl]ammonium] sulphate
EINECS(EC#)253-906-5
Molecular FormulaC₁₈H₂₉NO₂ . 1/2H₂O₄S
Molecular Weight340.47

Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x and SO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	384mg/kg (384mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 590, 1985.
mouse	LD50	intraperitoneal	71mg/kg (71mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.
mouse	LD50	intravenous	38mg/kg (38mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.
mouse	LD50	oral	1230mg/kg (1230mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.
mouse	LD50	subcutaneous	405mg/kg (405mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.
rabbit	LD50	intravenous	17mg/kg (17mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 590, 1985.
rabbit	LD50	oral	297mg/kg (297mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 590, 1985.
rat	LD50	intraperitoneal	76mg/kg (76mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.
rat	LD50	intravenous	26mg/kg (26mg/kg)		Yakkyoku. Pharmacy. Vol. 36, Pg. 657, 1985.
rat	LD50	oral	1350mg/kg (1350mg/kg)		Yakkyoku. Pharmacy. Vol. 36, Pg. 657, 1985.
rat	LD50	subcutaneous	860mg/kg (860mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 1001, 1981.