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Pregn-4-ene-3,20-dione,11,17-dihydroxy-21-(phosphonooxy)-, (11b)- cas no:3863-59-0

Synonyms: Corticosterone,17-hydroxy-, 21-phosphate (6CI); Cortisol, 21-(dihydrogen phosphate) (7CI,8CI);21-Hydrocortisonephosphoric acid; Corphos; Cortisol 21-monophosphate; Cortisol21-phosphate; Cortisol phosphate; Hydrocortisone 21-(dihydrogen phosphate);Hydrocortisone 21-phosphate; Hydrocortisone dihydrogen phosphate;Hydrocortisone phosphate; NSC 529660

Identification

NamePregn-4-ene-3,20-dione,11,17-dihydroxy-21-(phosphonooxy)-, (11b)-
CAS3863-59-0
SynonymsCorticosterone,17-hydroxy-, 21-phosphate (6CI); Cortisol, 21-(dihydrogen phosphate) (7CI,8CI);21-Hydrocortisonephosphoric acid; Corphos; Cortisol 21-monophosphate; Cortisol21-phosphate; Cortisol phosphate; Hydrocortisone 21-(dihydrogen phosphate);Hydrocortisone 21-phosphate; Hydrocortisone dihydrogen phosphate;Hydrocortisone phosphate; NSC 529660
EINECS(EC#)223-382-2
Molecular FormulaC21H31 O8 P
Molecular Weight442.49

Chemical Properties

refractive index1.596

Safety Data

Safety

Experimental teratogenic and reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of PO_x. See also HYDROCORTISONE-21-ACETATE; HYDROCORTISONE-17-BUTYRATE; HYDROCORTISONE-17-BUTYRATE-21-PROPIONATE; HYDROCORTISONE SODIUM SUCCINATE.

Toxicity

1.		ivn-rbt TDLo:900 mg/kg (female 8-16D post):TER		TJADAB Teratology, A Journal of Abnormal Development. 12 (1975),195.
2.		ivn-rbt TDLo:1800 mg/kg (8-16D preg):REP		TJADAB Teratology, A Journal of Abnormal Development. 12 (1972),195.

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