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5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-,(6R,7R)- cas no:38821-53-3

Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-, [6R-[6a,7b(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)-(9CI);7-[D-a-Amino-(1,4-cyclohexadienyl)acetamide]-3-desacetoxycephalosphoranicacid;Anspor;Cefradex;Cefradin;Cefradine;Cefrag;Cefro;Celex;Cephradin;Cephradine;Cesporan;Dimacef;Easkacef;Ecosporina;Eskacef;Lenzacef;Lisacef;Megacef;SQ 11436;Samedrin;Sefril;Velocef;Velosef;

Identification
Name5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-,(6R,7R)-
CAS38821-53-3
Synonyms5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-, [6R-[6a,7b(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)-(9CI);7-[D-a-Amino-(1,4-cyclohexadienyl)acetamide]-3-desacetoxycephalosphoranicacid;Anspor;Cefradex;Cefradin;Cefradine;Cefrag;Cefro;Celex;Cephradin;Cephradine;Cesporan;Dimacef;Easkacef;Ecosporina;Eskacef;Lenzacef;Lisacef;Megacef;SQ 11436;Samedrin;Sefril;Velocef;Velosef;
EINECS(EC#)254-137-8
Molecular FormulaC16H19N3O4S
Molecular Weight349.4
Chemical Properties
AppearanceSolid
refractive index1.684
storage tempStore at 0-5°C
Safety Data

Hazard Xi:Irritant
Risk R36/37/38;R42/43
Safety

Moderately toxic by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects: dermatitis. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
The Hazard Codes of Sefril (CAS NO.38821-53-3):IrritantXi,HarmfulXn
The Risk Statements information of SEFRIL(38821-53-3): 20/21/22-36/37/38-42/43
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R42/43:May cause sensitization by inhalation and skin contact.
The Safety Statements information of Sefril (CAS NO.38821-53-3): 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.?
RTECS XI0336000


Toxicity
1. ???

orl-wmn TDLo:5?mg/kg:SKN

??? CUTIBC ?? CUTIS; Cutaneous Medicine for the Practitioner. 38 (1986),58.
2. ???

orl-mus LD50:3549?mg/kg

??? NKRZAZ ?? Chemotherapy (Tokyo). 23 (1975),37.
3. ???

ipr-mus LD50:597?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680.
4. ???

scu-mus LD50:2890?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680.
5. ???

ivn-mus LD50:3539?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680.

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Leawell International Limited
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Tecoland Corporation
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Taizhou Orient Special Chemicals Co.
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Shreeji Pharma International
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King Tang Chemical Industry Group Co.,Ltd
Tel:86 519 8230 9998
Address: 7F, New Century Building, NO. 209 East Ave, Jintan, Changzhou 213200, Jiangsu, P.R.China
Keen Union International Limited
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Hangzhou Starshine Pharmaceutical Co., LTD
Tel:86-571-8696517
Address: Fengqi East Road, Hangzhou, China.

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