2-Pyridinecarboxylicacid,5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-,(4R)- cas no:3930-19-6

Name2-Pyridinecarboxylicacid,5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-,(4R)-
CAS3930-19-6
SynonymsPicolinicacid, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methyl-(7CI,8CI); (R)-Streptonigrin;5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinicacid; 5278RP; AO 50165L302; Abbott Crystalline antibiotic; Bruneomycin; NSC45383; NSC 56748; NSC 83950; Nigrin; Rufocromomycin; SN; STP; Streptonigran;Streptonigrin
EINECS(EC#)223-501-8
Molecular FormulaC25H22 N4 O8
Molecular Weight506.51

refractive index1.716
storage temp2-8°C

Hazardclass6.1(a)

Hazard T+: Very toxic;
Risk 28
Safety

A deadly poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: T+
Risk Statements: 28 
R28:Very toxic if swallowed.
Safety Statements: 53-28-36/37/39-45 
S53:Avoid exposure - obtain special instructions before use. 
S28:After contact with skin, wash immediately with plenty of soap-suds. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 3462 6.1/PG 1
WGK Germany: 3
RTECS: TJ7350000
F: 10-18
HazardClass: 6.1(a)
PackingGroup: II 

1.		mmo-sat 100 ng/plate		PNASA6    Proceedings of the National Academy of Sciences of the United States of America. 79 (1982),7445.
2.		mmo-bcs 600 µg/L		CMMUAO    Chemical Mutagens. Principles and Methods for Their Detection 9 (1984),165.
3.		ipr-rat LD50:150 µg/kg		FATOAO    Farmakologiya i Toksikologiya (Moscow). 37 (1974),197.
4.		orl-mus LD50:2330 µg/kg		ANTBAL    Antibiotiki. 12 (1967),132.
5.		ipr-mus LD50:520 µg/kg		FATOAO    Farmakologiya i Toksikologiya (Moscow). 37 (1974),197.
6.		scu-mus LD50:1000 µg/kg		COREAF    Comptes Rendus Hebdomadaires des Seances de lAcademie des Sciences. 261 (1965),4911.
7.		ivn-mus LD50:500 µg/kg		85ERAY    Antibiotics: Origin, Nature, and Properties. 2 (1978),1359.
8.		orl-dog LD50:500 µg/kg		ANTBAL    Antibiotiki. 11 (1966),1090.
9.		ivn-rat LD50:600 µg/kg		ANTBAL    Antibiotiki. 12 (1967),132.