396-01-0|TriamtereneProducts Supply - Chemical intermediates Network

Triamterene cas no:396-01-0

Synonyms: 2,4,7-Triamino-6-phenylpteridine; Triamterenum

Identification

NameTriamterene
CAS396-01-0
Synonyms2,4,7-Triamino-6-phenylpteridine; Triamterenum
EINECS(EC#)206-904-3
Molecular FormulaC12H11N7
Molecular Weight253.26

Chemical Properties

AppearanceYellow Solid
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard Xn:Harmful;
Risk R22;R36/37/38
Safety

Safety Information of Triamterene (CAS NO.396-01-0):
Hazard Codes: Xn Harmful ,T Toxic ,F Flammable
Risk Statements: 22-36/37/38-36/38-23/25
22: Harmful if swallowed
23: Toxic by inhalation
25: Toxic if swallowed
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
Safety Statements: 26-36/37/39-45-33-24-16-7
7: Keep container tightly closed
16: Keep away from sources of ignition - No smoking
24: Avoid contact with skin
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
33: Take precautionary measures against static discharges
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	249mg/kg (249mg/kg)		Drugs in Japan Vol. 6, Pg. 519, 1982.
mouse	LD50	intravenous	25077ug/kg (25.077mg/kg)		Pharmazie. Vol. 50, Pg. 419, 1995.
mouse	LD50	oral	285mg/kg (285mg/kg)		French Demande Patent Document. Vol. #2314719,
mouse	LD50	subcutaneous	620mg/kg (620mg/kg)		Drugs in Japan Vol. 6, Pg. 519, 1982.
mouse	LDLo	unreported	25mg/kg (25mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 35, Pg. 1688, 1985.
rat	LD50	intraperitoneal	200mg/kg (200mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 21, Pg. 775, 1979.
rat	LD50	oral	400mg/kg (400mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 21, Pg. 775, 1979.
women	TDLo	oral	42mg/kg/3W-I (42mg/kg)	LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"	Medical Journal of Australia. Vol. 147, Pg. 262, 1987.

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Triamterene cas no:396-01-0

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