dog |
LD50 |
intramuscular |
> 667mg/kg (667mg/kg) |
? |
Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977. |
dog |
LD50 |
intravenous |
383mg/kg (383mg/kg) |
? |
Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977. |
monkey |
LD50 |
intramuscular |
> 1335mg/kg (1335mg/kg) |
? |
Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977. |
mouse |
LD50 |
intramuscular |
1247mg/kg (1247mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Japanese Journal of Antibiotics. Vol. 39, Pg. 3164, 1986. |
mouse |
LD50 |
intraperitoneal |
2930mg/kg (2930mg/kg) |
? |
Japanese Journal of Antibiotics. Vol. 28, Pg. 415, 1975. |
mouse |
LD50 |
intravenous |
181mg/kg (181mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: ATAXIA |
Japanese Journal of Antibiotics. Vol. 39, Pg. 3164, 1986. |
mouse |
LD50 |
oral |
> 10679mg/kg (10679mg/kg) |
? |
Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977. |
mouse |
LD50 |
subcutaneous |
2470mg/kg (2470mg/kg) |
? |
Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977. |
rabbit |
LD50 |
intramuscular |
> 3gm/kg (3000mg/kg) |
? |
Japanese Journal of Antibiotics. Vol. 28, Pg. 415, 1975. |
rabbit |
LD50 |
intravenous |
248mg/kg (248mg/kg) |
? |
Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977. |
rabbit |
LD50 |
oral |
> 3gm/kg (3000mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 45, 1990. |
rat |
LD50 |
intramuscular |
2244mg/kg (2244mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Japanese Journal of Antibiotics. Vol. 39, Pg. 3164, 1986. |
rat |
LD50 |
intraperitoneal |
3500mg/kg (3500mg/kg) |
? |
Japanese Journal of Antibiotics. Vol. 28, Pg. 415, 1975. |
rat |
LD50 |
intravenous |
234mg/kg (234mg/kg) |
? |
Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977. |
rat |
LD50 |
oral |
> 4gm/kg (4000mg/kg) |
? |
Japanese Journal of Antibiotics. Vol. 28, Pg. 415, 1975. |
rat |
LD50 |
subcutaneous |
3604mg/kg (3604mg/kg) |
? |
Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977. |