39831-55-5|Amikacin disulfate saltProducts Supply - Chemical intermediates Network

Amikacin disulfate salt cas no:39831-55-5

Synonyms: 4)]-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)-,sulfate (1:2) (salt);4)]-N1-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-,sulfate (1:2) (salt) (9CI);Amiglyde V;Amika;Amikacin disulfate;Amikacinsulfate;Amikavet;Amikin;Amiklin;Antibiotic BB-K 8 sulfate;Biklin;Biodacyn;Fabianol;Grasil;Kaminax;Mikavir;Pierami;

Identification

NameAmikacin disulfate salt
CAS39831-55-5
Synonyms4)]-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)-,sulfate (1:2) (salt);4)]-N1-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-,sulfate (1:2) (salt) (9CI);Amiglyde V;Amika;Amikacin disulfate;Amikacinsulfate;Amikavet;Amikin;Amiklin;Antibiotic BB-K 8 sulfate;Biklin;Biodacyn;Fabianol;Grasil;Kaminax;Mikavir;Pierami;
EINECS(EC#)254-648-6
Molecular FormulaC₂₂H₄₃N₅O₁₃^.2(H₂SO₄)
Molecular Weight781.75948

Chemical Properties

AppearanceSolid
storage temp2-8°C

Safety Data

Hazard Xi
Risk R36/37/38
Safety

Poison by intravenous route. Moderately toxic by intraperitoneal and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NO_x and SO_x. See also?sulfates.
Hazard Codes:? Irritant Xi
The Risk Statements information of Antibiotic bb-k8 sulfate (CAS NO.39831-55-5):
36/37/38:? Irritating to eyes, respiratory system and skin?
The Safety Statements information of? Antibiotic bb-k8 sulfate (CAS NO.39831-55-5)?:
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:? Wear suitable protective clothing?
WGK Germany: 2
RTECS: WK1961200
F: 3-10

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intramuscular	> 667mg/kg (667mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977.
dog	LD50	intravenous	383mg/kg (383mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977.
monkey	LD50	intramuscular	> 1335mg/kg (1335mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977.
mouse	LD50	intramuscular	1247mg/kg (1247mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Japanese Journal of Antibiotics. Vol. 39, Pg. 3164, 1986.
mouse	LD50	intraperitoneal	2930mg/kg (2930mg/kg)	?	Japanese Journal of Antibiotics. Vol. 28, Pg. 415, 1975.
mouse	LD50	intravenous	181mg/kg (181mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA	Japanese Journal of Antibiotics. Vol. 39, Pg. 3164, 1986.
mouse	LD50	oral	> 10679mg/kg (10679mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977.
mouse	LD50	subcutaneous	2470mg/kg (2470mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977.
rabbit	LD50	intramuscular	> 3gm/kg (3000mg/kg)	?	Japanese Journal of Antibiotics. Vol. 28, Pg. 415, 1975.
rabbit	LD50	intravenous	248mg/kg (248mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977.
rabbit	LD50	oral	> 3gm/kg (3000mg/kg)	?	Drugs in Japan Vol. -, Pg. 45, 1990.
rat	LD50	intramuscular	2244mg/kg (2244mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Japanese Journal of Antibiotics. Vol. 39, Pg. 3164, 1986.
rat	LD50	intraperitoneal	3500mg/kg (3500mg/kg)	?	Japanese Journal of Antibiotics. Vol. 28, Pg. 415, 1975.
rat	LD50	intravenous	234mg/kg (234mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977.
rat	LD50	oral	> 4gm/kg (4000mg/kg)	?	Japanese Journal of Antibiotics. Vol. 28, Pg. 415, 1975.
rat	LD50	subcutaneous	3604mg/kg (3604mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 1, Pg. 125, 1977.

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Amikacin disulfate salt cas no:39831-55-5

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