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Oxirane,2-[(1-methylethoxy)methyl]- cas no:4016-14-2

Synonyms: Oxirane,[(1-methylethoxy)methyl]- (9CI); Propane, 1,2-epoxy-3-isopropoxy-(6CI,7CI,8CI); (Isopropoxymethyl)oxirane; (Isopropyloxymethyl)oxirane; (?à)-Glycidyl isopropyl ether;1,2-Epoxy-3-isopropoxypropane; 2,3-Epoxypropyl isopropyl ether;2-(Isopropoxymethyl)oxirane; 3-Isopropoxy-1,2-epoxypropane;3-Isopropyloxypropylene oxide; Glycidyl isopropyl ether; Isopropyl glycidylether; NSC 4127; NSC 46562; [(1-Methylethoxy)methyl]oxirane

Identification
NameOxirane,2-[(1-methylethoxy)methyl]-
CAS4016-14-2
SynonymsOxirane,[(1-methylethoxy)methyl]- (9CI); Propane, 1,2-epoxy-3-isopropoxy-(6CI,7CI,8CI); (Isopropoxymethyl)oxirane; (Isopropyloxymethyl)oxirane; (?à)-Glycidyl isopropyl ether;1,2-Epoxy-3-isopropoxypropane; 2,3-Epoxypropyl isopropyl ether;2-(Isopropoxymethyl)oxirane; 3-Isopropoxy-1,2-epoxypropane;3-Isopropyloxypropylene oxide; Glycidyl isopropyl ether; Isopropyl glycidylether; NSC 4127; NSC 46562; [(1-Methylethoxy)methyl]oxirane
EINECS(EC#)223-672-9
Molecular FormulaC6H12 O2
Molecular Weight116.18
Chemical Properties
Appearancecolourless liquid
refractive indexn20/D 1.410(lit.)
storage temp-20°C
Safety Data

Hazard Flammable liquid with flash p 92F (33.33C). TLV: TWA 50 ppm; STEL 75 ppm. Skin, eye, and respiratory irritant.
Risk R10
Safety

Hazard Codes:  Xi Irritant.
Risk Statements: 10-19-36/37/38-43
R10:  Flammable.
R19: May form explosive peroxides.
R36/37/38: Irritating to eyes, respiratory system and skin.
R43: May cause sensitization by skin contact.
Safety Statements: 16-26-36/37
S16: Keep away from sources of ignition-No smoking.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37: Wear suitable protective clothing and gloves.
RIDADR: UN 3271 3/PG 3
WGK: Germany 2
RTECS: TZ3500000
Suspected carcinogen. Moderately toxic by ingestion. Mildly toxic by inhalation and skin contact. A skin and eye irritant.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LC50 inhalation 1500ppm/4H (1500ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LIVER: OTHER CHANGES
AMA Archives of Industrial Health. Vol. 14, Pg. 250, 1956.
mouse LD50 oral 1300mg/kg (1300mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA
AMA Archives of Industrial Health. Vol. 14, Pg. 250, 1956.
rabbit LD50 skin 9650mg/kg (9650mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA AMA Archives of Industrial Health. Vol. 14, Pg. 250, 1956.
rat LC50 inhalation 1100ppm/8H (1100ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LIVER: OTHER CHANGES
AMA Archives of Industrial Health. Vol. 14, Pg. 250, 1956.
rat LD50 oral 4200mg/kg (4200mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA
AMA Archives of Industrial Health. Vol. 14, Pg. 250, 1956.

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