Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-,(1aS,8R,8aR,8bS)- cas no:4055-40-7
Synonyms: Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-8-(hydroxymethyl)-6-methoxy-1,5-dimethyl-,8-carbamate (8CI); Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-,[1aS-(1aa,8a,8aa,8ba)]-; Mitomycin B (7CI)
NameAzirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-,(1aS,8R,8aR,8bS)-
CAS4055-40-7
SynonymsAzirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-8-(hydroxymethyl)-6-methoxy-1,5-dimethyl-,8-carbamate (8CI); Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-,[1aS-(1aa,8a,8aa,8ba)]-; Mitomycin B (7CI)
Molecular FormulaC16H19 N3 O6
Molecular Weight349.38
refractive index1.674
Safety
Poison by intravenous route. Mutation data reported. When Mitomycin B (CAS NO.4055-40-7) is heated to decomposition ,it emits toxic fumes of NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
4500ug/kg (4.5mg/kg) |
|
Journal of Medicinal Chemistry. Vol. 36, Pg. 1461, 1993. |
| mouse |
LD50 |
intravenous |
3mg/kg (3mg/kg) |
|
Journal of Medicinal Chemistry. Vol. 14, Pg. 103, 1971. |
