40828-46-4|Benzeneacetic acid, a-methyl-4-(2-thienylcarbonyl)-Products Supply

Benzeneacetic acid, a-methyl-4-(2-thienylcarbonyl)- cas no:40828-46-4

Synonyms: (?à)-Suprofen;2-[4-(Thiophene-2-carbonyl)phenyl]propanoic acid; Masterfen; NSC 303611;Profenal; Profenol; R 25061; Racemic suprofen; Srendam; Sulproltin; Supranol;Suprocil; Suprofen; Suprol; Sutoprofen; TN 762; Topalgic;p-(2-Thenoyl)hydratropic acid

Identification

NameBenzeneacetic acid, a-methyl-4-(2-thienylcarbonyl)-
CAS40828-46-4
Synonyms(?à)-Suprofen;2-[4-(Thiophene-2-carbonyl)phenyl]propanoic acid; Masterfen; NSC 303611;Profenal; Profenol; R 25061; Racemic suprofen; Srendam; Sulproltin; Supranol;Suprocil; Suprofen; Suprol; Sutoprofen; TN 762; Topalgic;p-(2-Thenoyl)hydratropic acid
EINECS(EC#)255-096-9
Molecular FormulaC14H12 O3 S
Molecular Weight260.31

Chemical Properties

refractive index1.612
storage temp-20°C Freezer

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Safety

Poison by ingestion and intraperitoneal routes. Moderately toxic by subcutaneous route. Human systemic effects: changes in kidney tubules, hematuria. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SO_x. Used as an analgesic and anti-inflammatory agent.

Toxicity

1.	skn-rbt 150 mg/30D-I MLD	YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 15 (1987),3611.
2.	orl-man TDLo:8571 µg/kg/4D-I:KID	DICPBB Drug Intelligence and Clinical Pharmacy. 20 (1986),860.
3.	orl-man TDLo:2857 µg/kg:KID	AIMEAS Annals of Internal Medicine. 105 (1986),799.
4.	orl-wmn TDLo:4 mg/kg:KID	AIMEAS Annals of Internal Medicine. 106 (1987),235.
5.	orl-rat LD50:70,600 µg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 25 (1975),1526.
6.	ipr-rat LD50:335 mg/kg	YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 12 (1984),1005.
7.	scu-rat LD50:500 mg/kg	YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 12 (1984),1005.
8.	orl-mus LD50:590 mg/kg	DRFUD4 Drugs of the Future. 1 (1976),148.
9.	ipr-mus LD50:375 mg/kg	YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 12 (1984),1005.
10.	scu-mus LD50:710 mg/kg	YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 12 (1984),1005.

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Benzeneacetic acid, a-methyl-4-(2-thienylcarbonyl)- cas no:40828-46-4

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