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p-Toluenesulfonyl isocyanate cas no:4083-64-1

Synonyms: PTSI; Tosyl isocyanate; p-Toluenesulfonyl isocyanate

Identification
Namep-Toluenesulfonyl isocyanate
CAS4083-64-1
SynonymsPTSI; Tosyl isocyanate; p-Toluenesulfonyl isocyanate
EINECS(EC#)223-810-8
Molecular FormulaC8H7NO3S
Molecular Weight197.21
Chemical Properties
Appearanceclear liquid
refractive index1.533-1.535
storage tempStore in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water.
Sensitive Moisture Sensitive
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard Xn:Harmful
Risk R14;R36/37/38;R42
Safety

The Hazard Codes of?p-Toluene sulphonyl isocyanate (CAS NO.4083-64-1):? Xn
The Risk Statements information:?
14:? Reacts violently with water?
42:? May cause sensitization by inhalation?
36/37/38:? Irritating to eyes, respiratory system and skin?
The Safety Statements information:
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
28:? After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)?
30:? Never add water to this product?
RIDADR: UN 2206 6.1/PG 3
WGK Germany: 1
RTECS: DB9032000
F: 10
HazardClass:?? 6.1
PackingGroup:? III
Moderately toxic by ingestion and intraperitoneal routes. Low toxicity by inhalation. A mild skin and moderate eye irritant. When heated to decomposition it emits toxic vapors of NOx and SOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LC50 inhalation > 640ppm/1H (640ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
International Journal of Toxicology. Vol. 19, Pg. 368, 2000.
rat LD50 intraperitoneal 775mg/kg (775mg/kg) BEHAVIORAL: GENERAL ANESTHETIC International Journal of Toxicology. Vol. 19, Pg. 368, 2000.
rat LD50 oral 2234mg/kg (2234mg/kg) GASTROINTESTINAL: OTHER CHANGES International Journal of Toxicology. Vol. 19, Pg. 368, 2000.

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