41340-25-4|EtodolacProducts Supply - Chemical intermediates Network

Etodolac cas no:41340-25-4

Synonyms: 1,8-DIETHYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOLE-1-ACETIC ACID

Identification

NameEtodolac
CAS41340-25-4
Synonyms1,8-DIETHYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOLE-1-ACETIC ACID
EINECS(EC#)安全数据
Molecular FormulaC17H21NO3
Molecular Weight287.36

Chemical Properties

Appearancecrystalline solid
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard T:Toxic
Risk R23/24/25;R40
Safety

Hazard Codes:? Toxic T,? Irritant Xi
Risk Statements: 23/24/25-40-36-25-36/37/38?
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.?
R40: Limited evidence of a carcinogenic effect.?
R36: Irritating to eyes.?
R25: Toxic if swallowed.?
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 22-36-45-26-36/37?
S22: Do not breathe dust.?
S36: Wear suitable protective clothing.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37: Wear suitable protective clothing and gloves.
RIDADR: 3249
WGK Germany: 3
RTECS: UQ0360000
HazardClass: 6.1(b)
PackingGroup: III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	oral	> 4gm/kg (4000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: FOOD INTAKE (ANIMAL) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Oyo Yakuri. Pharmacometrics. Vol. 40, Pg. 469, 1990.
mouse	LD50	intraperitoneal	338mg/kg (338mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Oyo Yakuri. Pharmacometrics. Vol. 40, Pg. 469, 1990.
mouse	LD50	oral	593mg/kg (593mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Oyo Yakuri. Pharmacometrics. Vol. 40, Pg. 469, 1990.
mouse	LD50	subcutaneous	502mg/kg (502mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Oyo Yakuri. Pharmacometrics. Vol. 40, Pg. 469, 1990.
rat	LD50	intraperitoneal	100mg/kg (100mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Oyo Yakuri. Pharmacometrics. Vol. 40, Pg. 469, 1990.
rat	LD50	oral	94mg/kg (94mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Oyo Yakuri. Pharmacometrics. Vol. 40, Pg. 469, 1990.
rat	LD50	subcutaneous	113mg/kg (113mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Oyo Yakuri. Pharmacometrics. Vol. 40, Pg. 469, 1990.

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Etodolac cas no:41340-25-4

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