41372-08-1|L-Tyrosine, 3-hydroxy-a-methyl-, hydrate (2:3)Products Supply

L-Tyrosine, 3-hydroxy-a-methyl-, hydrate (2:3) cas no:41372-08-1

Synonyms: 3-Hydroxy-α-methyl-L-tyrosine hydrate (2:3);

Identification

NameL-Tyrosine, 3-hydroxy-a-methyl-, hydrate (2:3)
CAS41372-08-1
Synonyms3-Hydroxy-α-methyl-L-tyrosine hydrate (2:3);
EINECS(EC#)209-089-2
Molecular FormulaC₁₀H₁₃NO₄^.1.5(H₂O)
Molecular Weight238.27

Chemical Properties

AppearanceWhite Solid
storage tempRefrigerator

Safety Data

Risk 20/21-36/37/38-42/43-65
Safety Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YP2860000

CHEMICAL NAME :: L-Tyrosine, 3-hydroxy-alpha-methyl-, sesquihydrate

CAS REGISTRY NUMBER :: 41372-08-1

LAST UPDATED :: 199707

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H13-N-O4.3/2H2-O

MOLECULAR WEIGHT :: 238.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17500 mg/kg/14D-C

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 68250 mg/kg/13W-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - other changes

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 604 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2980 mg/kg

SEX/DURATION :: male 65 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - other effects on male Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989

supplier list

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

Epochem Co., Ltd.: Tel:+86-(21)-6760-1595; Address: Building No 7, Xinfei Road 1500, Songjiang Industrial Zone, Songjiang, Shanghai 201611,

Hangzhou Chiral Medicine Chemical Co Ltd: Tel:+86-(571)-82623231, 82638910; Address: 288 South Shi Xin Road, XiaoShan, Hangzhou 311200,

Hwasun Pharma: Tel:+86-(571)-82674539; Address: Qingchun Rd, Hangzhou, Zhejiang,

Alfa Aesar: Tel:+1-(978)-521-6300; Address: 26, Parkridge Road, Ward Hill, Massachusetts 01835,

Shanghai Hanhong Chemical Co., Ltd.: Tel:+86-(21)-64762736, 64531573; Address: 206-209, NO.1 Building , NO.245,Jiachuan Road, Xuhui District, Shanghai,

Beijing Medicine Chemical Trading Co. Ltd: Tel:+86-(10)-8870; Address: Xintai Building, No.8 Xiaguangli, Chaoyang, Beijing 100016,

Chemner Pharma: Tel:+86-(23)-62482345; Address: 668# International Exhibtion and Conference Center, Chongqing, Sichuan 400060,

ASDI Inc.: Tel:+1-(302)-266-6891, 888-577-2734; Address: 601 Interchange Blvd., Newark, Delaware 19711,

Trust & We Co., Ltd.: Tel:86-21-61551611; Address: 601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong, Shanghai, China.

Goly Chemical Co., Ltd.: Tel:+86-(632)-6163187; Address: Room No.6.Building21 LongXingBeiLi,ShiZhong, ZaoZhua, ShanDong 277102,

Hangzhou Sage Chemical Co., Ltd.: Tel:86-571-86818502; Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road

Shanghai Xunxin Chemical Co., Ltd: Tel:+86-(21)-38218795; Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315,

Hangzhou Lanpharma Co., Ltd.: Tel:+86-(571)-82877875; Address: Room 2-1908, Ningan Building,No.170,North Shixin Road, Xiaoshan, Hangzhou 311215,

Shanghai MEG Biochemical Co., Ltd.: Tel:+86-(21)-5108-2199; Address: 4-101 No.299 Bisheng Road, Zhangjiang Hi Tech Park, Shanghai 201204,

L-Tyrosine, 3-hydroxy-a-methyl-, hydrate (2:3) cas no:41372-08-1

Directory

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

supplier list