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2-Aza-8-germaspiro[4.5]decane-2-propanamine,8,8-diethyl-N,N-dimethyl-, hydrochloride (1:2) cas no:41992-22-7

Synonyms: 2-Aza-8-germaspiro[4.5]decane-2-propanamine,8,8-diethyl-N,N-dimethyl-, dihydrochloride (9CI); NSC 192-965; Spirogermanium32; Spirogermanium hydrochloride

Identification
Name2-Aza-8-germaspiro[4.5]decane-2-propanamine,8,8-diethyl-N,N-dimethyl-, hydrochloride (1:2)
CAS41992-22-7
Synonyms2-Aza-8-germaspiro[4.5]decane-2-propanamine,8,8-diethyl-N,N-dimethyl-, dihydrochloride (9CI); NSC 192-965; Spirogermanium32; Spirogermanium hydrochloride
Molecular FormulaC17H36 Ge N2 . 2 Cl H
Molecular Weight414.06
Safety Data

Safety

Poison by subcutaneous, intramuscular, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx and HCl. See also GERMANIUM COMPOUNDS.


Toxicity
1.    

ipr-rat LD50:107 mg/kg

    NCISP*    National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 .
2.    

scu-rat LD50:210 mg/kg

    NCISP*    National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 .
3.    

ivn-mus LD50:41,500 µg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB264-117 .
4.    

ims-mus LD50:119 mg/kg

    CTRRDO    Cancer Treatment Reports. 64 (1980),1207.
5.    

ivn-dog LDLo:40 mg/kg

    CTRRDO    Cancer Treatment Reports. 64 (1980),1207.
6.    

ims-dog LDLo:40 mg/kg

    CTRRDO    Cancer Treatment Reports. 64 (1980),1207.

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