42399-41-7|1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S,3S)-Products Supply

1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S,3S)- cas no:42399-41-7

Synonyms: 1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S-cis)-;(+)-Diltiazem;(+)-cis-Diltiazem;Balcor;Cartia XT;Coras;Dilzem;Dilzem retard;d-Diltiazem;d-cis-Diltiazem;

Identification

Name1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S,3S)-
CAS42399-41-7
Synonyms1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S-cis)-;(+)-Diltiazem;(+)-cis-Diltiazem;Balcor;Cartia XT;Coras;Dilzem;Dilzem retard;d-Diltiazem;d-cis-Diltiazem;
EINECS(EC#)255-796-4
Molecular FormulaC₂₂H₂₆N₂O₄S
Molecular Weight414.52

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	68mg/kg (68mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE BLOOD: CHANGES IN PLATELET COUNT	Journal of Toxicology, Clinical Toxicology. Vol. 33, Pg. 273, 1995.
mouse	LD50	intravenous	61mg/kg (61mg/kg)	?	Japanese Journal of Toxicology. Vol. 4, Pg. 121, 1991.
mouse	LD50	oral	740mg/kg (740mg/kg)	?	Japanese Journal of Toxicology. Vol. 4, Pg. 121, 1991.
mouse	LDLo	intraperitoneal	220mg/kg (220mg/kg)	?	Indian Journal of Experimental Biology. Vol. 34, Pg. 1194, 1996.

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1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S,3S)- cas no:42399-41-7

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