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1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S,3S)- cas no:42399-41-7

Synonyms: 1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S-cis)-;(+)-Diltiazem;(+)-cis-Diltiazem;Balcor;Cartia XT;Coras;Dilzem;Dilzem retard;d-Diltiazem;d-cis-Diltiazem;

Identification
Name1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S,3S)-
CAS42399-41-7
Synonyms1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S-cis)-;(+)-Diltiazem;(+)-cis-Diltiazem;Balcor;Cartia XT;Coras;Dilzem;Dilzem retard;d-Diltiazem;d-cis-Diltiazem;
EINECS(EC#)255-796-4
Molecular FormulaC22H26N2O4S
Molecular Weight414.52
Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 68mg/kg (68mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE

BLOOD: CHANGES IN PLATELET COUNT
Journal of Toxicology, Clinical Toxicology. Vol. 33, Pg. 273, 1995.
mouse LD50 intravenous 61mg/kg (61mg/kg) ? Japanese Journal of Toxicology. Vol. 4, Pg. 121, 1991.
mouse LD50 oral 740mg/kg (740mg/kg) ? Japanese Journal of Toxicology. Vol. 4, Pg. 121, 1991.
mouse LDLo intraperitoneal 220mg/kg (220mg/kg) ? Indian Journal of Experimental Biology. Vol. 34, Pg. 1194, 1996.

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