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N-ethyl-n'-nitro-n-nitrosoguanidine cas no:4245-77-6

Synonyms: N-ETHYL-N'-NITRO-N-NITROSOGUANIDINE;1-ethyl-3-nitro-1-nitroso-guanidin;n-aethyl-n’-nitro-n-nitrosoguanidin;n-ethyl-n-nitroso-n’-nitroguanidine;nsc38191;1-ETHYL-3-NITRO-1-NITROSOGUANIDINE;ENNG;1-ETHYL-1-NITROSO-3-NITROGUANIDINE

Identification
NameN-ethyl-n'-nitro-n-nitrosoguanidine
CAS4245-77-6
SynonymsN-ETHYL-N'-NITRO-N-NITROSOGUANIDINE;1-ethyl-3-nitro-1-nitroso-guanidin;n-aethyl-n’-nitro-n-nitrosoguanidin;n-ethyl-n-nitroso-n’-nitroguanidine;nsc38191;1-ETHYL-3-NITRO-1-NITROSOGUANIDINE;ENNG;1-ETHYL-1-NITROSO-3-NITROGUANIDINE
EINECS(EC#)224-206-7
Molecular FormulaC3H7N5O3
Molecular Weight161.12
Chemical Properties
refractive index1.613
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass4.1
Safety Data

Hazard F,T
Risk 45-46-11-23/24/25
Safety

Questionable carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Safety Information about N-ethyl-n'-nitro-n-nitrosoguanidine (CAS NO.4245-77-6):
Hazard Codes: 
F: T:
Risk Statements about N-ethyl-n'-nitro-n-nitrosoguanidine (CAS NO.4245-77-6):
R45: May cause cancer.
R46: May cause heritable genetic damage.
R11: Highly Flammable.
R23/24/25:   Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements about N-ethyl-n'-nitro-n-nitrosoguanidine (CAS NO.4245-77-6):
S53: Avoid exposure - obtain special instruction before use.
S16: Keep away from sources of ignition - No smoking.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
RIDADR: 1325
RTECS: MF2465000
HazardClass: 4.1
PackingGroup: III


Toxicity
1.    

mma-sat 5 µg/plate

    TCMUE9    Topics in Chemical Mutagenesis. 1 (1984),13.
2.    

mmo-esc 2 µg/plate

    KSRNAM    Kiso to Rinsho. Clinical Report. 19 (1985),4465.
3.    

pic-esc 200 µg/L

    TCMUE9    Topics in Chemical Mutagenesis. 1 (1984),91.
4.    

sce-hmn:lym 1 µmol/L

    NGCJAK    Nippon Gan Chiryo Gakkai-shi. Journal of Japan Society for Cancer Therapy. 15 (1980),1085.
5.    

dnd-ham:ovr 20 µmol/L

    MUREAV    Mutation Research. 132 (1984),41.
6.    

sce-ham-orl 10 mg/kg

    MUREAV    Mutation Research. 113 (1983),33.
7.    

sce-ham:lng 10 mg/L

    CNREA8    Cancer Research. 44 (1984),3270.

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