4291-63-8|CladribineProducts Supply - Chemical intermediates Network

Cladribine cas no:4291-63-8

Synonyms: 2-Chloro-2-deoxy-beta-adenosine;2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine;Chlorodeoxyadenosine;RWJ 26251;Adenosine,2-chloro-2'-deoxy-;Leustatin;24757-90-2;2-CdA;2-Chlorodeoxyadenosine;Adenosine, 2-chloro-2-deoxy;Cladribine(Base);Cadribine;Leustatin (TN);Cladribine [USAN:BAN:INN];2-Chloro-2-deoxyadenosine;

Identification

NameCladribine
CAS4291-63-8
Synonyms2-Chloro-2-deoxy-beta-adenosine;2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine;Chlorodeoxyadenosine;RWJ 26251;Adenosine,2-chloro-2'-deoxy-;Leustatin;24757-90-2;2-CdA;2-Chlorodeoxyadenosine;Adenosine, 2-chloro-2-deoxy;Cladribine(Base);Cadribine;Leustatin (TN);Cladribine [USAN:BAN:INN];2-Chloro-2-deoxyadenosine;
EINECS(EC#)224-427-9
Molecular FormulaC₁₀H₁₂ClN₅O₃
Molecular Weight285.69

Chemical Properties

AppearanceWhite Crystalline Solid
storage temp2-8°C

Safety Data

Hazard T:Toxic
Risk R23/24/25;R36/37/38
Safety

Hazard Codes:? Toxic T
Risk Statements: 36/37/38-23/24/25
R36/37/38:Irritating to eyes, respiratory system and skin.?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-37/39-45-36-22?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S37/39:Wear suitable gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36:Wear suitable protective clothing.?
S22:Do not breathe dust.
WGK Germany: 3
RTECS: AU7357560

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	intravenous	700ug/kg/7D-C (0.7mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	American Journal of Hematology. Vol. 53, Pg. 209, 1996.
mouse	LD50	intraperitoneal	150mg/kg (150mg/kg)	?	Leukemia and Lymphoma. Vol. 5, Pg. 1, 1991.

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Cladribine cas no:4291-63-8

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