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Cladribine cas no:4291-63-8

Synonyms: 2-Chloro-2-deoxy-beta-adenosine;2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine;Chlorodeoxyadenosine;RWJ 26251;Adenosine,2-chloro-2'-deoxy-;Leustatin;24757-90-2;2-CdA;2-Chlorodeoxyadenosine;Adenosine, 2-chloro-2-deoxy;Cladribine(Base);Cadribine;Leustatin (TN);Cladribine [USAN:BAN:INN];2-Chloro-2-deoxyadenosine;

Identification
NameCladribine
CAS4291-63-8
Synonyms2-Chloro-2-deoxy-beta-adenosine;2-Chloro-6-amino-9-(2-deoxy-beta-D-erythropentofuranosyl)purine;Chlorodeoxyadenosine;RWJ 26251;Adenosine,2-chloro-2'-deoxy-;Leustatin;24757-90-2;2-CdA;2-Chlorodeoxyadenosine;Adenosine, 2-chloro-2-deoxy;Cladribine(Base);Cadribine;Leustatin (TN);Cladribine [USAN:BAN:INN];2-Chloro-2-deoxyadenosine;
EINECS(EC#)224-427-9
Molecular FormulaC10H12ClN5O3
Molecular Weight285.69
Chemical Properties
AppearanceWhite Crystalline Solid
storage temp2-8°C
Safety Data

Hazard T:Toxic
Risk R23/24/25;R36/37/38
Safety

Hazard Codes:?ToxicT
Risk Statements: 36/37/38-23/24/25
R36/37/38:Irritating to eyes, respiratory system and skin.?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-37/39-45-36-22?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S37/39:Wear suitable gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36:Wear suitable protective clothing.?
S22:Do not breathe dust.
WGK Germany: 3
RTECS: AU7357560


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo intravenous 700ug/kg/7D-C (0.7mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" American Journal of Hematology. Vol. 53, Pg. 209, 1996.
mouse LD50 intraperitoneal 150mg/kg (150mg/kg) ? Leukemia and Lymphoma. Vol. 5, Pg. 1, 1991.

supplier list

Tianjin Harmony Technology Development Co., Ltd.
Tel:
Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
ZunAn Commerce & Industrial Co., Ltd.
Tel:锛?86-755-82910159, 82910995,82910996
Address: Room 3007, United Plaza A, Binhe Road 5022, Shenzhen, P.R.China
Hangzhou Coben Pharmaceutical Co.,Ltd.
Tel:+86-571-28021577 28021578
Address: Nanyang Economical Development Zone,Zhejiang
HANGZHOU THINK CHEMICAL CO., LTD.
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Address: ROOM 719 BUILDING D MEIDU PLAZA 789 MOGANSHAN ROAD HANGZHOU CHINA
J.INC.
Tel:+91 79 30903703
Address: 303, 3rd Floor, Royale Manor, Law Garden,Ellisbridge, Ahmedabad - 380006,Gujarat, India
Shanghai Chemhere Co., Ltd.
Tel:+86-(21)-26607989
Address: Unit 602, No.14,Ziwei Rd, Zhangjiang High-tech Park, Shanghai,
Shanghai Richem International Co., Ltd.
Tel:+86-(21)-31263688
Address: Room 603, Golden Eagle Mansion A, No.1518 Minsheng Road, Pudong, Shanghai 200135,
Axitec Co., Ltd.
Tel:+86-(755)-26491310
Address: 1415 HuiXiu Building,HuiBing Square, DongBing Road, Shenzhen, Guangdong 518068,
Shanghai Yudiao Chemistry Technology Co., Ltd.
Tel:+86-(21)-57962550
Address: Shanghai Torch Innovation Park of Fine Chemical Industry, Building A, NO.688,Qiushi Road,Jinshan Dis, Shanghai 201512,
Shangai Maxchemco Chemical Industry Limited
Tel:+86-(21)-54822160
Address: No.1305-8, B241, The Ecust Park, Huajing Road, Xuhui, Shanghai,
Fox Chemicals GmbH
Tel:+49-(7240)-927151
Address: Bockstalstr.10 A, Pfinztal D-76327,
Tecoland Corporation
Tel:+1-(732)-603-9577
Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,
Conier Chem & Pharma Co.,Ltd.
Tel:+86-(23)-62922305
Address: 24 South Section 1, Yihuan Road, Chengdu, Sichuan 610065,
Goly Chemical Co., Ltd.
Tel:+86-(632)-6163187
Address: Room No.6.Building21 LongXingBeiLi,ShiZhong, ZaoZhua, ShanDong 277102,
Hangzhou Sage Chemical Co., Ltd.
Tel:86-571-86818502
Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road

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