Carbamicacid, N-[6-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester cas no:43210-67-9

NameCarbamicacid, N-[6-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester
CAS43210-67-9
SynonymsCarbamicacid, [5-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester (9CI);2-(Methoxycarbonylamino)-5-(phenylthio)benzimidazole;Axilur;Fenbendazol;Fenbion;HOE 881;Methyl5-(phenylthio)-2-benzimidazolecarbamate;Methyl[5-(phenylthio)-1H-benzimidazol-2-yl]carbamate;Panacur;Safe-Guard;
EINECS(EC#)256-145-7
Molecular FormulaC₁₅H₁₃N₃O₂S
Molecular Weight299.34762

Appearancewhite to yellowish powder
refractive index1.709
storage temp0-6°C

Hazard UN NO.
Risk R36/37/38
Safety Hazard Codes:Xi
Risk Statements:36/37/38
36/37/38:Irritating to eyes, respiratory system and skin
Safety Statements:26-36
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:Wear suitable protective clothing
WGK Germany:2

CHEMICAL IDENTIFICATION

RTECS NUMBER :

DD6520500

CHEMICAL NAME :

2-Benzimidazolecarbamic acid, 5-(phenylthio)-, methyl ester

CAS REGISTRY NUMBER :

43210-67-9

LAST UPDATED :

199606

DATA ITEMS CITED :

12

MOLECULAR FORMULA :

C15-H13-N3-O2-S

MOLECULAR WEIGHT :

299.37

WISWESSER LINE NOTATION :

T56 BM DNJ CMVO1 GSR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>10 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>1250 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>2 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

>10 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

>500 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - pig

DOSE/DURATION :

>5 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - domestic

DOSE/DURATION :

>5 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

42 gm/kg/14D-I

TOXIC EFFECTS :

Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :

Mutation test systems - not otherwise specified

TEST SYSTEM :

Human Cells - not otherwise specified

DOSE/DURATION :

2 mg/L

REFERENCE :

THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 31,505,1976