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9H-Pyrido[3,4-b]indole,7-methoxy-1-methyl- cas no:442-51-3

Synonyms: 1-Methyl-7-methoxy-b-carboline;7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole;Banisterin;Banisterine;Harmin;Leucoharmine;Telepathin;Telepathine;Yagein;Yageine;

Identification
Name9H-Pyrido[3,4-b]indole,7-methoxy-1-methyl-
CAS442-51-3
Synonyms1-Methyl-7-methoxy-b-carboline;7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole;Banisterin;Banisterine;Harmin;Leucoharmine;Telepathin;Telepathine;Yagein;Yageine;
EINECS(EC#)207-131-4
Molecular FormulaC13H12N2O
Molecular Weight212.27
Chemical Properties
AppearanceOff-white solid
refractive index1.706
storage tempRefrigerator
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard Xn:Harmful
Risk R20/21/22;R36
Safety

Poison by intravenous and subcutaneous routes. Human systemic effects by intramuscular route: sleep disturbance, tremors, nausea. When heated to decomposition it emits toxic fumes of NOx.Safety information of Banisterine monohydrate (CAS NO.442-51-3):
Hazard Codes??HarmfulXn
Risk Statements?
25 Toxic if swallowed
36 Irritating to the eyes
20/21/22 Harmful by inhalation, in contact with skin and if swallowed
Safety Statements?
22 Do not breathe dust
24/25 Avoid contact with skin and eyes
36/37 Wear suitable protective clothing and gloves
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
RIDADR? 1544
WGK Germany? 3
RTECS? UV0175000
HazardClass? 6.1
PackingGroup? III


Toxicity
1. ???

ims-man TDLo:3?mg/kg:CNS,GIT

??? AEPPAE ?? Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 129 (1928),133.
2. ???

scu-mus LD50:243?mg/kg

??? PCJOAU ?? Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 10 (1976),1171.
3. ???

ivn-mus LDLo:50?mg/kg

??? AEPPAE ?? Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 129 (1928),133.
4. ???

ivn-rat LDLo:10?mg/kg

??? AEPPAE ?? Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 129 (1928),133.
5. ???

scu-rbt LDLo:200?mg/kg

??? AEPPAE ?? Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 129 (1928),133.
6. ???

ivn-rbt LDLo:60?mg/kg

??? NEPHBW ?? Neuropharmacology. 10 (1971),15.
7. ???

scu-gpg LDLo:100?mg/kg

??? AEPPAE ?? Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 129 (1928),133.
8. ???

scu-frg LDLo:300?mg/kg

??? QJPPAL ?? Quarterly Journal of Pharmacy and Pharmacology. 9 (1936),37.

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