Coumermycin cas no:4434-05-3

NameCoumermycin
CAS4434-05-3
Synonymscoumamycin;coumermycins;iyl)bis(carbonylimino))bis(7-((5,5-di-c-methyl-4-o-methyl-alpha-l-lyxopyranosy;l)oxy)-4-hydroxy-8-methylcoumarin);notomycina1;pyrrole-2-carboxylicacid,5-methyl-,diesterwith3,3’-((3-methylpyrrole-2,4-d;COUMERMYCIN A1;Coumermycin
Molecular FormulaC55H59N5O20
Molecular Weight1110.08

refractive index1.684

Hazard Xn
Risk 22
Safety

Poison by subcutaneous, intramuscular, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.

Hazard CodesXn
Risk Statements 22
R22: Coumermycin A1 (CAS NO.4434-05-3) is harmful if swallowed.
Safety Statements 36
S36:Wear suitable protective clothing.
WGK Germany 3
RTECS UX9375000
F 10-21

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intramuscular	500mg/kg (500mg/kg)		"Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 147, 1978.
mouse	LD50	intraperitoneal	159mg/kg (159mg/kg)		"Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 147, 1978.
mouse	LD50	intravenous	25mg/kg (25mg/kg)		"Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 147, 1978.
mouse	LD50	oral	2gm/kg (2000mg/kg)		"Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 147, 1978.
mouse	LD50	subcutaneous	250mg/kg (250mg/kg)		Antimicrobial Agents and Chemotherapy Vol. -, Pg. 786, 1965.