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Angiotensin II,5-L-isoleucine- cas no:4474-91-3

Synonyms: Angiotensin II, human (Octapeptide);Alanine,N-[1-[N-[N-[N-[N-(N2-L-a-aspartyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-isoleucyl]-L-histidyl]-L-prolyl]-3-phenyl-,L- (6CI,7CI);

Identification
NameAngiotensin II,5-L-isoleucine-
CAS4474-91-3
SynonymsAngiotensin II, human (Octapeptide);Alanine,N-[1-[N-[N-[N-[N-(N2-L-a-aspartyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-isoleucyl]-L-histidyl]-L-prolyl]-3-phenyl-,L- (6CI,7CI);
Molecular FormulaC50H71N13O12
Molecular Weight1046.34
Chemical Properties
refractive index1.663
storage temp−20°C
Safety Data

Safety

A poison by intravenous route. Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx.
WGK Germany of Angiotensin II, human (CAS NO.4474-91-3): 3


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 30800ug/kg (30.8mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 6079, 1990.
rat LD50 intravenous 17400ug/kg (17.4mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 6079, 1990.

 

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