11H-Dibenzo[b,e][1,4]diazepin-11-one,10-[2-(dimethylamino)ethyl]-5,10-dihydro-5-methyl- cas no:4498-32-2

Name11H-Dibenzo[b,e][1,4]diazepin-11-one,10-[2-(dimethylamino)ethyl]-5,10-dihydro-5-methyl-
CAS4498-32-2
Synonyms10-[2-(Dimethylamino)ethyl]-5,10-dihydro-5-methyl-11H-dibenzo[b,e][1,4]diazepin-11-one;Dibenzepin; Dibenzepine
Molecular FormulaC18H21 N3 O
Molecular Weight295.37

refractive index1.592
storage tempRefrigerator

Hazardclass6.1(b)

Safety

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Many dibenz-azepine compounds have central nervous system effects. When heated to decomposition Dibenzepin (CAS NO.4498-32-2) emits toxic fumes of NO_x. See also DIAZEPAM.

1.		orl-rat LD50:220 mg/kg		INPHB6    International Pharmacopsychiatry. 1 (1968),214.
2.		ipr-rat LD50:70 mg/kg		INPHB6    International Pharmacopsychiatry. 1 (1968),214.
3.		scu-rat LD50:542 mg/kg		IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 6 (1975),119.
4.		ivn-rat LD50:22 mg/kg		INPHB6    International Pharmacopsychiatry. 1 (1968),214.
5.		orl-mus LD50:194 mg/kg		IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 6 (1975),119.
6.		ipr-mus LD50:60 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 21 (1971),1727.
7.		scu-mus LD50:90 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 19 (1969),458.
8.		ivn-mus LD50:22 mg/kg		INPHB6    International Pharmacopsychiatry. 1 (1968),214.