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4-Aminotrifluorotoluene cas no:455-14-1

Synonyms: 4-Aminobenzotrifluoride; p-Trifluoromethylaniline; trifluoromehylphenylanilide; 4-trifluoromethyl aniline; 4-(Trifluoromethyl) aniline; 4-Amino Trifluorotoluene;

Identification
Name4-Aminotrifluorotoluene
CAS455-14-1
Synonyms4-Aminobenzotrifluoride; p-Trifluoromethylaniline; trifluoromehylphenylanilide; 4-trifluoromethyl aniline; 4-(Trifluoromethyl) aniline; 4-Amino Trifluorotoluene;
EINECS(EC#)207-236-5
Molecular FormulaC7H6F3N
Molecular Weight161.12
Chemical Properties
AppearanceClear yellow liquid.
refractive index1.483-1.485
storage tempKeep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard Xn:Harmful
Risk R20/21/22;R33;R36/37/38
Safety Hazard Codes:T,N,Xi,Xn
Risk Statements:25-36-50/53-36/37/38-33-20/21/22
25:Toxic if swallowed
36:Irritating to the eyes
50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
36/37/38:Irritating to eyes, respiratory system and skin
33:Danger of cumulative effects
20/21/22:Harmful by inhalation, in contact with skin and if swallowed
Safety Statements:26-45-60-61-36/37/39-36
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
60:This material and/or its container must be disposed of as hazardous waste
61:Avoid release to the environment. Refer to special instructions safety data sheet
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
36:Wear suitable protective clothing
RIDADR:UN 2810 6.1/PG 3
WGK Germany:3
HazardClass:6.1
PackingGroup:III
Hazard Note:Toxic/Irritant
HS Code:29214300

HS Code 29214300

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XU9260000
CHEMICAL NAME :
p-Toluidine, alpha,alpha,alpha-trifluoro-
CAS REGISTRY NUMBER :
455-14-1
BEILSTEIN REFERENCE NO. :
1564853
LAST UPDATED :
199709
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C7-H6-F3-N
MOLECULAR WEIGHT :
161.14
WISWESSER LINE NOTATION :
ZR CXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
101 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
58 mg/kg/3D-I
TOXIC EFFECTS :
Endocrine - changes in spleen weight Blood - changes in bone marrow (not otherwise specified) Blood - changes in erythrocyte (RBC) count

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
10 mg/L
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5,803,1983

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