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Fenalamide cas no:4551-59-1

Synonyms: Benzeneacetic acid, a-[[[2-(diethylamino)ethyl]amino]carbonyl]-a-ethyl-, ethyl ester; Malonamicacid, N-[2-(diethylamino)ethyl]-2-ethyl-2-phenyl-, ethyl ester (6CI,7CI,8CI); Ethyl N-(2-diethylaminoethyl)-2-phenyl-2-ethylmalononamate; EthylN-[2-(N',N'-dimethylamino)-ethyl]-2-ethyl-2-phenylmalonamate; EthylN-[2-(diethylamino)ethyl]-2-ethyl-2-phenylmalonamate; Femamide;Phemamide; SH 30858; Sch 5706; Spasmamide

Identification
NameFenalamide
CAS4551-59-1
SynonymsBenzeneacetic acid, a-[[[2-(diethylamino)ethyl]amino]carbonyl]-a-ethyl-, ethyl ester; Malonamicacid, N-[2-(diethylamino)ethyl]-2-ethyl-2-phenyl-, ethyl ester (6CI,7CI,8CI); Ethyl N-(2-diethylaminoethyl)-2-phenyl-2-ethylmalononamate; EthylN-[2-(N',N'-dimethylamino)-ethyl]-2-ethyl-2-phenylmalonamate; EthylN-[2-(diethylamino)ethyl]-2-ethyl-2-phenylmalonamate; Femamide;Phemamide; SH 30858; Sch 5706; Spasmamide
EINECS(EC#)224-917-2
Molecular FormulaC19H30 N2 O3
Molecular Weight331.37
Chemical Properties
refractive index1.505
Safety Data

Safety

A human poison by ingestion. Poison experimentally by ingestion, subcutaneous, intraperitoneal, and rectal routes. Human systemic effects by ingestion: interstitial nephritis, metabolic acidosis, dermatitis, agranulocytosis. An experimental teratogen. Other experimental reproductive effects. When Feldene (CAS NO.4551-59-1) is heated to decomposition, it emits toxic fumes of SOx and NOx.


Toxicity

  Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 210mg/kg (210mg/kg)   Bollettino Chimico Farmaceutico. Vol. 111, Pg. 293, 1972.
mouse LD50 oral 400mg/kg (400mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 237, Pg. 264, 1959.
rat LD50 intraperitoneal 250mg/kg (250mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 237, Pg. 264, 1959.
rat LD50 oral 610mg/kg (610mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 237, Pg. 264, 1959.

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