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Safety
A human poison by ingestion. Poison experimentally by ingestion, subcutaneous, intraperitoneal, and rectal routes. Human systemic effects by ingestion: interstitial nephritis, metabolic acidosis, dermatitis, agranulocytosis. An experimental teratogen. Other experimental reproductive effects. When Feldene (CAS NO.4551-59-1) is heated to decomposition, it emits toxic fumes of SOx and NOx.
Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source | |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 210mg/kg (210mg/kg) | Bollettino Chimico Farmaceutico. Vol. 111, Pg. 293, 1972. | |
mouse | LD50 | oral | 400mg/kg (400mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 237, Pg. 264, 1959. | |
rat | LD50 | intraperitoneal | 250mg/kg (250mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 237, Pg. 264, 1959. | |
rat | LD50 | oral | 610mg/kg (610mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 237, Pg. 264, 1959. |
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