2-Dimethylaminoethyl chloride hydrochloride cas no:4584-46-7
Synonyms: 2-Chloro-N,N-dimethylethylamine hydrochloride; 2-Dimethylaminoethyl chloride HCL (DMC, HCl); 1-Chloro-2-(dimethylamino)ethane hydrochloride; N-(2-Chloroethyl)-N,N-dimethylammonium chloride; 2-chloroethyldimethylammonium chloride
Name2-Dimethylaminoethyl chloride hydrochloride
CAS4584-46-7
Synonyms2-Chloro-N,N-dimethylethylamine hydrochloride; 2-Dimethylaminoethyl chloride HCL (DMC, HCl); 1-Chloro-2-(dimethylamino)ethane hydrochloride; N-(2-Chloroethyl)-N,N-dimethylammonium chloride; 2-chloroethyldimethylammonium chloride
EINECS(EC#)224-970-1
Molecular FormulaC4H10ClN?HCl;C4H11Cl2N
Molecular Weight144.04
AppearanceColorless to beige crystal
storage tempKeep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Sensitive Hygroscopic
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Hazard T+:Verytoxic;N:Dangerousfortheenvironment;
Risk R22;R24;R26;R36/37/38;R51/53;R68
Safety
Safety Information of 2-Dimethylaminoethyl chloride hydrochloride (CAS NO.4584-46-7):
Hazard Codes: 
T,T+ 
N
Risk Statements: 22-24-36/37/38-68-51/53-26
R22: Harmful if swallowed.
R24: Toxic in contact with skin.
R26: Very toxic by inhalation.
R68: Possible risk of irreversible effects.
R36/37/38: Irritating to eyes, respiratory system and skin.
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 26-45-61-36/37/39-28
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28: After contact with skin, wash immediately with plenty of soap-suds.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: KQ9020000
HazardClass: 6.1
PackingGroup: III
HS Code: 9211980
Poison by intraperitoneal and subcutaneous routes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
HS Code 29211980
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| guinea pig |
LDLo |
skin |
250mg/kg (250mg/kg) |
|
National Technical Information Service. Vol. OTS0546424, |
| mouse |
LD50 |
intraperitoneal |
280mg/kg (280mg/kg) |
BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES
GASTROINTESTINAL: OTHER CHANGES |
Cancer Vol. 2, Pg. 1055, 1949. |
| mouse |
LD50 |
subcutaneous |
250mg/kg (250mg/kg) |
|
Journal of Pharmacology and Experimental Therapeutics. Vol. 97, Pg. 25, 1949. |
| rabbit |
LD50 |
skin |
290mg/kg (290mg/kg) |
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BLOOD: HEMORRHAGE
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" |
National Technical Information Service. Vol. OTS0539178, |
| rat |
LD50 |
oral |
238mg/kg (238mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: TREMOR
BEHAVIORAL: ATAXIA |
National Technical Information Service. Vol. OTS0546424, |
