Mepicycline penicillinate cas no:4599-60-4

NameMepicycline penicillinate
CAS4599-60-4
SynonymsPenimepicycline [INN:DCF];Penimepicycline;4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-N-((4-(2-hydroxyethyl)-1-piperazinyl)methyl)-6-methyl-1,11-dioxo-2-naphthacenecarboxamide salt with phenoxymethylpenicillin;Duamine;Hydrocycline;Mepicycline penicillinate;Penetracyne;Penimepiciclina;Penimepiciclina [DCIT];Penimepicyclinum;Penimepicyclinum [INN-Latin];4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6- (2-phenoxyacetamido)-, compd. with 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-N-((4-(2-hydroxyethyl)-1-piperazinyl)methyl)-6-methyl-1,11-dioxo-2-naphthacenecarboxamide (1:1);(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - (2Z,4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-2-[hydroxy({[4-(2-hydroxyethyl)piperazin-1-yl]methyl}amino)methylidene]-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione (1:1)
EINECS(EC#)225-002-0
Molecular FormulaC29H38N4O9 . C16H18N2O5S
Molecular Weight937.0229

Safety

Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. When heated to decomposition, Mepicycline penicillinate (CAS NO.4599-60-4) emits toxic fumes of NO_x and SO_x.

1.		orl-rat LD50:3990 mg/kg		GNRIDX    Gendai no Rinsho. 2 (1968),26.
2.		scu-rat LD50:1550 mg/kg		GNRIDX    Gendai no Rinsho. 2 (1968),26.
3.		ivn-rat LD50:345 mg/kg		GNRIDX    Gendai no Rinsho. 2 (1968),26.
4.		orl-mus LD50:3 g/kg		GNRIDX    Gendai no Rinsho. 2 (1968),26.
5.		scu-mus LD50:1096 mg/kg		GNRIDX    Gendai no Rinsho. 2 (1968),26.
6.		ivn-mus LD50:342 mg/kg		GNRIDX    Gendai no Rinsho. 2 (1968),26.