465-39-4|Bufa-20,22-dienolide,14,15-epoxy-3-hydroxy-, (3b,5b,15b)-Products Supply

Bufa-20,22-dienolide,14,15-epoxy-3-hydroxy-, (3b,5b,15b)- cas no:465-39-4

Synonyms: 5b-Bufa-20,22-dienolide, 14,15b-epoxy-3b-hydroxy- (6CI,7CI,8CI);14,15b-Epoxy-3b-hydroxy-5b-bufa-20,22-dienolide;3b-Hydroxy-14,15b-epoxy-5b-bufa-20,22-dienolide;Bufogenin;NSC 90783;Recibufogenin;Resi;Resibufogenin;Respigon;

Identification

NameBufa-20,22-dienolide,14,15-epoxy-3-hydroxy-, (3b,5b,15b)-
CAS465-39-4
Synonyms5b-Bufa-20,22-dienolide, 14,15b-epoxy-3b-hydroxy- (6CI,7CI,8CI);14,15b-Epoxy-3b-hydroxy-5b-bufa-20,22-dienolide;3b-Hydroxy-14,15b-epoxy-5b-bufa-20,22-dienolide;Bufogenin;NSC 90783;Recibufogenin;Resi;Resibufogenin;Respigon;
Molecular FormulaC₂₄H₃₂O₄
Molecular Weight384.50848

Chemical Properties

AppearanceWhite to off-white solid.
refractive index1.602
storage tempStore in original container in a cool dark place.

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(a)

Safety Data

Safety

Deadly poison by intravenous route. When heated to decomposition it emits acrid smoke and fumes. See also BUFOGENIN B.
RIDADR: 3172
HazardClass: 6.1(a)
PackingGroup: II

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
frog	LD50	parenteral	7830ug/kg (7.83mg/kg)	?	Drugs of the Future. Vol. 12, Pg. 837, 1987.
mouse	LD50	intraperitoneal	14mg/kg (14mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 1239, 1982.
mouse	LD50	intravenous	4250ug/kg (4.25mg/kg)	?	Drugs in Japan Vol. 6, Pg. 899, 1982.
mouse	LD50	oral	59800mg/kg (59800mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 1239, 1982.
mouse	LD50	subcutaneous	104mg/kg (104mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 1239, 1982.
rat	LD50	intravenous	2200ug/kg (2.2mg/kg)	?	Drugs in Japan Vol. 6, Pg. 899, 1982.
rat	LD50	parenteral	21mg/kg (21mg/kg)	?	Drugs of the Future. Vol. 12, Pg. 837, 1987.

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Bufa-20,22-dienolide,14,15-epoxy-3-hydroxy-, (3b,5b,15b)- cas no:465-39-4

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