Morpholine,2-[(2-ethoxyphenoxy)methyl]- cas no:46817-91-8

Synonyms: (?à)-2-(o-Ethoxyphenoxymethyl)morpholine;2-(2-Ethoxyphenoxymethyl)morpholine; Emovit; Viloxazin; Viloxazine

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Identification
Chemical Properties
Safety Data
Toxicity

Identification

NameMorpholine,2-[(2-ethoxyphenoxy)methyl]-
CAS46817-91-8
Synonyms(?à)-2-(o-Ethoxyphenoxymethyl)morpholine;2-(2-Ethoxyphenoxymethyl)morpholine; Emovit; Viloxazin; Viloxazine
EINECS(EC#)256-281-7
Molecular FormulaC13H19 N O3
Molecular Weight237.33

Chemical Properties

refractive index1.499

Safety Data

Safety

Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x. See also VILOXAZINE HYDROCHLORIDE.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	60mg/kg (60mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Handbook of Experimental Pharmacology. Vol. 55, Pg. 527, 1980.
mouse	LD50	oral	552mg/kg (552mg/kg)		European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 27, Pg. 437, 1992.
rat	LD50	intravenous	60mg/kg (60mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Handbook of Experimental Pharmacology. Vol. 55, Pg. 527, 1980.
rat	LD50	oral	2gm/kg (2000mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Handbook of Experimental Pharmacology. Vol. 55, Pg. 527, 1980.

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