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Home > products > Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-,(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-

Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-,(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)- cas no:469-59-0

Synonyms: Jervine(8CI); Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3b,23b)-; Jervin; NSC 23898; NSC 7520;Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-,[3S-(3a,6aa,6bb,9a(3'S*,3'aR*,6'R*,7'aS*),11ab,11ba)]-

Identification
NameSpiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-,(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-
CAS469-59-0
SynonymsJervine(8CI); Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3b,23b)-; Jervin; NSC 23898; NSC 7520;Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-,[3S-(3a,6aa,6bb,9a(3'S*,3'aR*,6'R*,7'aS*),11ab,11ba)]-
EINECS(EC#)207-417-9
Molecular FormulaC27H39 N O3
Molecular Weight425.67
Chemical Properties
refractive index1.59
storage temp−20°C
Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. A natural toxin found in some plants. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:  Xn Harmful
Risk Statements:  22 
R22:Harmful if swallowed.
RIDADR:  UN 2811 6.1/PG 3
WGK Germany:  3
RTECS:  WG9700000


Toxicity
1.    

orl-rbt TDLo:66,700 µg/kg (female 7D post):TER

    PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 136 (1971),1174.
2.    

orl-rat LDLo:240 mg/kg

    PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 149 (1975),302.
3.    

orl-mus LDLo:180 mg/kg

    PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 149 (1975),302.
4.    

scu-mus LD50:29 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 113 (1955),89.
5.    

ivn-mus LD50:9300 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 82 (1944),167.
6.    

orl-ham LDLo:80 mg/kg

    TJADAB    Teratology, A Journal of Abnormal Development. 17 (1978),327.

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