4697-14-7|4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)-Products Supply

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)- cas no:4697-14-7

Synonyms: 3-Thiophenemalonamicacid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-,disodium salt (7CI,8CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2a,5a,6b)]-;Aerugipen;Ticillin;Ticarcilline disodium;

Identification

Name4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)-
CAS4697-14-7
Synonyms3-Thiophenemalonamicacid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-,disodium salt (7CI,8CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2a,5a,6b)]-;Aerugipen;Ticillin;Ticarcilline disodium;
Molecular FormulaC₁₅H₁₄N₂Na₂O₆S₂
Molecular Weight428.391

Chemical Properties

AppearanceCrystalline Powde
storage temp2-8°C

Safety Data

Hazard Xi:Irritant;
Risk R36/37/38;R42;R43
Safety

Mildly toxic by ingestion. An experimental teratogen. When heated to decomposition it emits toxic fumes of SO_x, NO_x, and Na₂O.
Hazard Codes: Xn,Xi
Risk Statements:
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
42: During fumigation/spraying wear suitable respiratory equipment (appropriate wording to be specified)
43: May cause sensitization by skin contact
Safety Statements:
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37: Wear suitable gloves

Toxicity

dog	LD50	intravenous	> 4gm/kg (4000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: NAUSEA OR VOMITING	Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
dog	LD50	subcutaneous	7gm/kg (7000mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
mouse	LD50	intraperitoneal	7800mg/kg (7800mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE KIDNEY, URETER, AND BLADDER: OTHER CHANGES	Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
mouse	LD50	intravenous	5200mg/kg (5200mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
mouse	LD50	oral	> 16gm/kg (16000mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
mouse	LD50	subcutaneous	10700mg/kg (10700mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
rabbit	LD50	intravenous	> 8gm/kg (8000mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
rabbit	LD50	subcutaneous	> 11gm/kg (11000mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
rat	LD50	intraperitoneal	7200mg/kg (7200mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
rat	LD50	intravenous	5350mg/kg (5350mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) KIDNEY, URETER, AND BLADDER: OTHER CHANGES	Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
rat	LD50	oral	16gm/kg (16000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.
rat	LD50	subcutaneous	10gm/kg (10000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978.

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4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)- cas no:4697-14-7

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