Chenodeoxycholic acid cas no:474-25-9
Synonyms: Anthropodeoxycholic acid;Cholan-24-oic acid,3,7-dihydroxy-,(3R,5a,- 7R)-;Chenodiol [USAN];7-alpha-Hydroxylithocholic acid;Anthropododesoxycholic acid;Acido chenodeoxicholico [INN-Spanish];Chenodesoxycholic acid;Cholan-24-oic acid, 3,7-dihydroxy-, (3-.alpha., 5-.beta., 7-.alpha.)-;Acidum chenodeoxycholicum [INN-Latin];Anthropodesoxycholic acid;Chenodeoxycholic acid (JAN);(4R)-4-[(3R,5S,7R,8R,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate;Chendol;3-alpha,7-alpha-Dihydroxy-5-beta-cholan-24-oic acid;Prestwick_553;3-alpha,7-alpha-Dihydroxycholanic acid;Cholan-24-oic acid, 3,7-dihydroxy-, (3-alpha,5-beta,7-alpha)- (9CI);Chenodiol;Chenodesoxycholsaeure [German];5-beta-Cholan-24-oic acid, 3-alpha,7-alpha-dihydroxy-;(4R)-4-[(3R,5S,7R,8S,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;Chenodeoxycholate;
NameChenodeoxycholic acid
CAS474-25-9
SynonymsAnthropodeoxycholic acid;Cholan-24-oic acid,3,7-dihydroxy-,(3R,5a,- 7R)-;Chenodiol [USAN];7-alpha-Hydroxylithocholic acid;Anthropododesoxycholic acid;Acido chenodeoxicholico [INN-Spanish];Chenodesoxycholic acid;Cholan-24-oic acid, 3,7-dihydroxy-, (3-.alpha., 5-.beta., 7-.alpha.)-;Acidum chenodeoxycholicum [INN-Latin];Anthropodesoxycholic acid;Chenodeoxycholic acid (JAN);(4R)-4-[(3R,5S,7R,8R,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate;Chendol;3-alpha,7-alpha-Dihydroxy-5-beta-cholan-24-oic acid;Prestwick_553;3-alpha,7-alpha-Dihydroxycholanic acid;Cholan-24-oic acid, 3,7-dihydroxy-, (3-alpha,5-beta,7-alpha)- (9CI);Chenodiol;Chenodesoxycholsaeure [German];5-beta-Cholan-24-oic acid, 3-alpha,7-alpha-dihydroxy-;(4R)-4-[(3R,5S,7R,8S,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;Chenodeoxycholate;
EINECS(EC#)207-481-8
Molecular FormulaC24H40O4
Molecular Weight392.58
Appearancewhite to off-white crystalline powder
alpha12 o (C=1, CHCL3)
refractive index1.558
storage tempStore in a cool, dry place. Store in a tightly closed container.
Hazard Xn:Harmful
Risk R63
Safety
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Questionable human carcinogen producing liver tumors. Mutation data reported. When heated to decomposition it emits acrid smoke and fumes.
Hazard Codes:?
Xn
Risk Statements: 63?
R63:Possible risk of harm to the unborn child.
Safety Statements: 22-24/25-45-36/37?
S22:Do not breathe dust.?
S24/25:Avoid contact with skin and eyes.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37:Wear suitable protective clothing and gloves.
WGK Germany: 2
RTECS: FZ1980000
| 1. |
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mmo-sat 20?mg/L
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MUREAV ?? Mutation Research. 158 (1985),45. |
| 2. |
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sln-smc 100?mg/L
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CRNGDP ?? Carcinogenesis. 5 (1984),447. |
| 3. |
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orl-wmn TDLo:24?g/kg/5Y-C:CAR
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CLONEA ?? Clinics in Oncology. 7 (1981),245. |
| 4. |
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orl-rat LD50:4000?mg/kg
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IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 13 (1982),1128. |
| 5. |
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ipr-rat LD50:105?mg/kg
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OYYAA2 ?? Oyo Yakuri. Pharmacometrics. 15 (1978),915. |
| 6. |
??? |
ivn-rat LD50:106?mg/kg
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OYYAA2 ?? Oyo Yakuri. Pharmacometrics. 15 (1978),915. |
| 7. |
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orl-mus LD50:3000?mg/kg
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IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 13 (1982),1128. |
| 8. |
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ipr-mus LD50:86?mg/kg
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OYYAA2 ?? Oyo Yakuri. Pharmacometrics. 15 (1978),915. |
| 9. |
??? |
ivn-mus LD50:100?mg/kg
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ARZNAD ?? Arzneimittel-Forschung. Drug Research. 20 (1970),323. |
