2H-Benzimidazol-2-one,5-chloro-1-[3-(dimethylamino)propyl]-1,3-dihydro-3-phenyl- cas no:4755-59-3

Name2H-Benzimidazol-2-one,5-chloro-1-[3-(dimethylamino)propyl]-1,3-dihydro-3-phenyl-
CAS4755-59-3
Synonyms2-Benzimidazolinone,5-chloro-1-[3-(dimethylamino)propyl]-3-phenyl- (7CI,8CI); Clodazon
Molecular FormulaC18H20 Cl N3 O
Molecular Weight329.86

refractive index1.609

Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When Clodazone (CAS NO.4755-59-3) is heated to decomposition, it emits toxic fumes of Cl⁻ and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	505mg/kg (505mg/kg)		International Pharmacopsychiatry. Vol. 1, Pg. 214, 1968.
mouse	LD50	intravenous	90mg/kg (90mg/kg)		International Pharmacopsychiatry. Vol. 1, Pg. 214, 1968.
mouse	LD50	oral	715mg/kg (715mg/kg)		International Pharmacopsychiatry. Vol. 1, Pg. 214, 1968.
rat	LD50	intraperitoneal	142mg/kg (142mg/kg)		International Pharmacopsychiatry. Vol. 1, Pg. 214, 1968.
rat	LD50	intravenous	77mg/kg (77mg/kg)		International Pharmacopsychiatry. Vol. 1, Pg. 214, 1968.
rat	LD50	oral	2gm/kg (2000mg/kg)		International Pharmacopsychiatry. Vol. 1, Pg. 214, 1968.