Chelidonine cas no:476-32-4
Synonyms: Chelidonine(6CI,7CI,8CI); [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-13-methyl-, [5bR-(5ba,6b,12ba)]-; (+)-Chelidonine; Chelidonin;Stylophorine; [5bR-(5ba,6b,12ba)]-5b,6,7,12b,13,14-Hexahydro-13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol
NameChelidonine
CAS476-32-4
SynonymsChelidonine(6CI,7CI,8CI); [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-13-methyl-, [5bR-(5ba,6b,12ba)]-; (+)-Chelidonine; Chelidonin;Stylophorine; [5bR-(5ba,6b,12ba)]-5b,6,7,12b,13,14-Hexahydro-13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol
EINECS(EC#)207-504-1
Molecular FormulaC20H19NO5
Molecular Weight353.37
refractive index1.667
storage temp2-8°C
Hazard
Xn
Risk R20/21/22;R25
Safety
Hazard Codes: Xn .gif)
Risk Statements: 25-20/21/22
25: Chelidonine (476-32-4) is toxic if swallowed
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
Safety Statements: 20-45-36/37
20:When using, do not eat or drink
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37:Chelidonine (476-32-4) used,Wear suitable protective clothing and gloves
RIDADR: 2811
RTECS : FL9450000
Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
cat |
LD50 |
subcutaneous |
140mg/kg (140mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 135, 1960.
|
dog |
LD50 |
subcutaneous |
500mg/kg (500mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 135, 1960.
|
frog |
LD50 |
subcutaneous |
160mg/kg (160mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 135, 1960.
|
mouse |
LD50 |
intravenous |
35mg/kg (35mg/kg) |
|
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 5, Pg. 163, 1946. |
mouse |
LD50 |
subcutaneous |
125mg/kg (125mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 135, 1960.
|
mouse |
LD50 |
unreported |
2750mg/kg (2750mg/kg) |
|
Herba Polonica. Vol. 25, Pg. 209, 1979. |
rabbit |
LD50 |
subcutaneous |
360mg/kg (360mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 135, 1960.
|