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Chelidonine cas no:476-32-4

Synonyms: Chelidonine(6CI,7CI,8CI); [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-13-methyl-, [5bR-(5ba,6b,12ba)]-; (+)-Chelidonine; Chelidonin;Stylophorine; [5bR-(5ba,6b,12ba)]-5b,6,7,12b,13,14-Hexahydro-13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol

Identification
NameChelidonine
CAS476-32-4
SynonymsChelidonine(6CI,7CI,8CI); [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-13-methyl-, [5bR-(5ba,6b,12ba)]-; (+)-Chelidonine; Chelidonin;Stylophorine; [5bR-(5ba,6b,12ba)]-5b,6,7,12b,13,14-Hexahydro-13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol
EINECS(EC#)207-504-1
Molecular FormulaC20H19NO5
Molecular Weight353.37
Chemical Properties
refractive index1.667
storage temp2-8°C
Safety Data

Hazard Xn
Risk R20/21/22;R25
Safety

Hazard Codes:  Xn
Risk Statements: 25-20/21/22
25:  Chelidonine (476-32-4) is toxic if swallowed 
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
Safety Statements:  20-45-36/37
20:When using, do not eat or drink
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37:Chelidonine (476-32-4) used,Wear suitable protective clothing and gloves
RIDADR:  2811
RTECS : FL9450000
 


Toxicity

 

 

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 subcutaneous 140mg/kg (140mg/kg)  

Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 135, 1960.
 

 

dog LD50 subcutaneous 500mg/kg (500mg/kg)  

Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 135, 1960.
 

 

frog LD50 subcutaneous 160mg/kg (160mg/kg)  

Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 135, 1960.
 

 

mouse LD50 intravenous 35mg/kg (35mg/kg)   Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 5, Pg. 163, 1946.
mouse LD50 subcutaneous 125mg/kg (125mg/kg)  

Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 135, 1960.
 

 

mouse LD50 unreported 2750mg/kg (2750mg/kg)   Herba Polonica. Vol. 25, Pg. 209, 1979.
rabbit LD50 subcutaneous 360mg/kg (360mg/kg)  

Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 135, 1960.
 

 

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