Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R,5aS,8aR,9R)- cas no:477-47-4

NameFuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R,5aS,8aR,9R)-
CAS477-47-4
SynonymsFuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, [5R-(5a,5aa,8aa,9a)]-; Picropodophyllin(6CI,7CI,8CI); NSC 36407; Picropodophyllotoxin
Molecular FormulaC22H22 O8
Molecular Weight414.44

refractive index1.605
storage temp2-8°C

Hazard Xi,T
Risk 36/37/38-68-25-21
Safety

A poison by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard Codes Xi,T
Risk Statements 36/37/38-68-25-21
R21:Harmful in contact with skin. 
R25 :Toxic if swallowed. 
R68:Possible risk of irreversible effects. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-36-45-36/37
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37:Wear suitable protective clothing and gloves.
RIDADR UN 3462 6.1/PG 2
WGK Germany 3
RTECS LV2510000

 

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	280mg/kg (280mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951.