platyphylline cas no:480-78-4

Nameplatyphylline
CAS480-78-4
Synonymsplatyphylline;(1R)-1,2-Dihydro-12-hydroxysenecionan-11,16-dione;[1R,(-)]-1,2-Dihydro-12-hydroxysenecionan-11,16-dione;Platifillin;(1-alpha)-1,2-Dihydro-12-hydroxysenecionan-11,16-dione;66641-38-1 (Hydrochloride);Einecs 207-558-6;Platiphillin
EINECS(EC#)207-558-6
Molecular FormulaC18H27NO5
Molecular Weight337.413

refractive index1.553

Hazardclass6.1(b)

Hazard Moderately toxic by ingestion.
Safety

A poison by intraperitoneal and intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NO_x.
RIDADR 1544
HazardClass 6.1(b)
PackingGroup III

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	577mg/kg (577mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toksikologicheskii Vestnik. Vol. (1), Pg. 34, 1997.
mouse	LD50	intravenous	105mg/kg (105mg/kg)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" BLOOD: "LYMPHOMA, INCLUDING HODGKIN'S DISEASE"	Research Today. Vol. 5, Pg. 53, 1949.
mouse	LD50	oral	2573mg/kg (2573mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toksikologicheskii Vestnik. Vol. (1), Pg. 34, 1997.
rat	LD50	intraperitoneal	252mg/kg (252mg/kg)		Australian Journal of Experimental Biology and Medical Science. Vol. 46, Pg. 493, 1968.
rat	LD50	intravenous	60mg/kg (60mg/kg)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" BLOOD: "LYMPHOMA, INCLUDING HODGKIN'S DISEASE"	Research Today. Vol. 5, Pg. 53, 1949.
rat	LD50	oral	3100mg/kg (3100mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toksikologicheskii Vestnik. Vol. (1), Pg. 34, 1997.