[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-,(3Z,6R,14aR,14bR)- cas no:480-81-9

Name[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-,(3Z,6R,14aR,14bR)-
CAS480-81-9
SynonymsSenecionan-11,16-dione,13,19-didehydro-12-hydroxy-; Seneciphylline (6CI,7CI,8CI); Jacodine; NSC 30622;Seneciophylline; Seneciphyllin;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione,3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-,[6R-(3Z,6R*,14aR*,14bR*)]-; a-Longilobine
Molecular FormulaC18H23 N O5
Molecular Weight333.38

Appearancewhite powder
refractive index1.581

Hazardclass6.1(b)

Risk R23/24/25
Safety

A poison by intravenous route. Questionable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
Risk Statements: 23/24/25 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements: 1-20-24/25-45
S1 :Keep locked up. 
S20:When using, do not eat or drink. 
S24/25:Avoid contact with skin and eyes. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: 1544
HazardClass: 6.1(b)
PackingGroup: III 

1.		dns-rat:lvr 1 µmol/L		CNREA8    Cancer Research. 45 (1985),3125.
2.		dns-ham:lvr 1 µmol/L		CNREA8    Cancer Research. 45 (1985),3125.
3.		ivn-rat LD50:80 mg/kg		RETOAE    Research Today. 5 (1949),53.
4.		ivn-mus LD50:90 mg/kg		RETOAE    Research Today. 5 (1949),53.