4800-94-6|4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(2-carboxy-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)-Products Supply

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(2-carboxy-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)- cas no:4800-94-6

Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2a,5a,6b)]-;Malonamic acid,N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-2-phenyl-,disodium salt (7CI,8CI);Anabactyl;BRL 2064;CP 15639-2;Carbapen;Carbecin;Carbenicillin disodium salt;Carbenicillin sodium;Carbenicilline disodium;Carboxybenzylpenicillin sodium;Disodium (a-carboxybenzyl)penicillin;Disodium carbenicillin;Fugacillin;Geopen;Hyoper;Microcillin;Piopen;Pyopen;Sodium carbenicillin;a-Carboxybenzylpenicillin disodiumsalt;a-Carboxybenzylpenicillin sodiumsalt;

Identification

Name4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(2-carboxy-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)-
CAS4800-94-6
Synonyms4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2a,5a,6b)]-;Malonamic acid,N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-2-phenyl-,disodium salt (7CI,8CI);Anabactyl;BRL 2064;CP 15639-2;Carbapen;Carbecin;Carbenicillin disodium salt;Carbenicillin sodium;Carbenicilline disodium;Carboxybenzylpenicillin sodium;Disodium (a-carboxybenzyl)penicillin;Disodium carbenicillin;Fugacillin;Geopen;Hyoper;Microcillin;Piopen;Pyopen;Sodium carbenicillin;a-Carboxybenzylpenicillin disodiumsalt;a-Carboxybenzylpenicillin sodiumsalt;
EINECS(EC#)225-360-8
Molecular FormulaC₁₇H₁₆N₂Na₂O₆S
Molecular Weight424.41

Chemical Properties

AppearanceAlmost white solid.
storage temp2-8°C

Safety Data

Hazard Xn:Harmful
Risk R42/43
Safety

Mildly toxic by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NO_x, Na₂O, and SO_x. See also CARBENICILLIN PHENYL SODIUM.
Safety Information of Carbenicillin sodium (CAS NO.4800-94-6):
Hazard Codes: Xn
Risk Statements: 42/43
42:? May cause sensitization by inhalation?
43:? May cause sensitization by skin contact
Safety Statements: 22-36/37-36
22:? Do not breathe dust
36:? Wear suitable protective clothing??
37:? Wear suitable gloves?

HS Code 29411000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 4gm/kg (4000mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
dog	LD50	subcutaneous	> 4gm/kg (4000mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
monkey	LD50	intravenous	9800mg/kg (9800mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 34, Pg. 405, 1975.
mouse	LD50	intracrebral	95500ug/kg (95.5mg/kg)	?	Chemotherapy Vol. 17, Pg. 1111, 1969.
mouse	LD50	intraperitoneal	7600mg/kg (7600mg/kg)	?	Drugs in Japan Vol. 6, Pg. 187, 1982.
mouse	LD50	intravenous	4500mg/kg (4500mg/kg)	?	Chemotherapy Vol. 23, Pg. 572, 1975.
mouse	LD50	oral	> 12gm/kg (12000mg/kg)	?	Chemotherapy Vol. 23, Pg. 572, 1975.
mouse	LD50	subcutaneous	9gm/kg (9000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 187, 1982.
rabbit	LD50	intravenous	> 4gm/kg (4000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
rabbit	LD50	subcutaneous	> 4gm/kg (4000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
rat	LD50	intraperitoneal	10gm/kg (10000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 187, 1982.
rat	LD50	intravenous	6800mg/kg (6800mg/kg)	?	Drugs in Japan Vol. 6, Pg. 187, 1982.
rat	LD50	oral	> 10gm/kg (10000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 187, 1982.
rat	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 187, 1982.

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4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(2-carboxy-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)- cas no:4800-94-6

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