4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(2-carboxy-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)- cas no:4800-94-6
Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2a,5a,6b)]-;Malonamic acid,N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-2-phenyl-,disodium salt (7CI,8CI);Anabactyl;BRL 2064;CP 15639-2;Carbapen;Carbecin;Carbenicillin disodium salt;Carbenicillin sodium;Carbenicilline disodium;Carboxybenzylpenicillin sodium;Disodium (a-carboxybenzyl)penicillin;Disodium carbenicillin;Fugacillin;Geopen;Hyoper;Microcillin;Piopen;Pyopen;Sodium carbenicillin;a-Carboxybenzylpenicillin disodiumsalt;a-Carboxybenzylpenicillin sodiumsalt;
Name4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(2-carboxy-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-, sodium salt(1:2), (2S,5R,6R)-
CAS4800-94-6
Synonyms4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2a,5a,6b)]-;Malonamic acid,N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-2-phenyl-,disodium salt (7CI,8CI);Anabactyl;BRL 2064;CP 15639-2;Carbapen;Carbecin;Carbenicillin disodium salt;Carbenicillin sodium;Carbenicilline disodium;Carboxybenzylpenicillin sodium;Disodium (a-carboxybenzyl)penicillin;Disodium carbenicillin;Fugacillin;Geopen;Hyoper;Microcillin;Piopen;Pyopen;Sodium carbenicillin;a-Carboxybenzylpenicillin disodiumsalt;a-Carboxybenzylpenicillin sodiumsalt;
EINECS(EC#)225-360-8
Molecular FormulaC17H16N2Na2O6S
Molecular Weight424.41
AppearanceAlmost white solid.
storage temp2-8°C
Hazard Xn:Harmful
Risk R42/43
Safety
Mildly toxic by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx, Na2O, and SOx. See also CARBENICILLIN PHENYL SODIUM.
Safety Information of Carbenicillin sodium (CAS NO.4800-94-6):
Hazard Codes: Xn.gif)
Risk Statements: 42/43
42:? May cause sensitization by inhalation?
43:? May cause sensitization by skin contact
Safety Statements: 22-36/37-36
22:? Do not breathe dust
36:? Wear suitable protective clothing??
37:? Wear suitable gloves?
HS Code 29411000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LD50 |
intravenous |
> 4gm/kg (4000mg/kg) |
GASTROINTESTINAL: NAUSEA OR VOMITING |
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969. |
| dog |
LD50 |
subcutaneous |
> 4gm/kg (4000mg/kg) |
GASTROINTESTINAL: NAUSEA OR VOMITING |
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969. |
| monkey |
LD50 |
intravenous |
9800mg/kg (9800mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 34, Pg. 405, 1975. |
| mouse |
LD50 |
intracrebral |
95500ug/kg (95.5mg/kg) |
? |
Chemotherapy Vol. 17, Pg. 1111, 1969. |
| mouse |
LD50 |
intraperitoneal |
7600mg/kg (7600mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 187, 1982. |
| mouse |
LD50 |
intravenous |
4500mg/kg (4500mg/kg) |
? |
Chemotherapy Vol. 23, Pg. 572, 1975. |
| mouse |
LD50 |
oral |
> 12gm/kg (12000mg/kg) |
? |
Chemotherapy Vol. 23, Pg. 572, 1975. |
| mouse |
LD50 |
subcutaneous |
9gm/kg (9000mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 187, 1982. |
| rabbit |
LD50 |
intravenous |
> 4gm/kg (4000mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE |
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969. |
| rabbit |
LD50 |
subcutaneous |
> 4gm/kg (4000mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE |
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969. |
| rat |
LD50 |
intraperitoneal |
10gm/kg (10000mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 187, 1982. |
| rat |
LD50 |
intravenous |
6800mg/kg (6800mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 187, 1982. |
| rat |
LD50 |
oral |
> 10gm/kg (10000mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 187, 1982. |
| rat |
LD50 |
subcutaneous |
> 10gm/kg (10000mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 187, 1982. |
