Naphtho[1,2-b]furan-2,8(3H,4H)-dione,3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, (3S,3aS,5aS,9bS)- cas no:481-06-1
Synonyms: Eudesma-1,4-dien-12-oicacid, 6a-hydroxy-3-oxo-, g-lactone, (11S)- (8CI);Naphtho[1,2-b]furan-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-,[3S-(3a,3aa,5ab,9bb)]-; (-)-Santonin; (-)-a-Santonin;1,2,3,4,4a,7-Hexahydro-1-hydroxy-a,4a,8-trimethyl-7-oxo-2-naphthaleneacetic acid g-lactone; NSC 4900; Santonin; Semenen; a-Santonin
NameNaphtho[1,2-b]furan-2,8(3H,4H)-dione,3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, (3S,3aS,5aS,9bS)-
CAS481-06-1
SynonymsEudesma-1,4-dien-12-oicacid, 6a-hydroxy-3-oxo-, g-lactone, (11S)- (8CI);Naphtho[1,2-b]furan-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-,[3S-(3a,3aa,5ab,9bb)]-; (-)-Santonin; (-)-a-Santonin;1,2,3,4,4a,7-Hexahydro-1-hydroxy-a,4a,8-trimethyl-7-oxo-2-naphthaleneacetic acid g-lactone; NSC 4900; Santonin; Semenen; a-Santonin
EINECS(EC#)207-560-7
Molecular FormulaC15H18 O3
Molecular Weight246.33
refractive index-172.5 ° (C=2, CHCl3)
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Hazard Toxic by ingestion, affects color vision.
Risk R22
Safety
Human poison by an unspecified route. Experimental poison by intravenous route. Moderately toxic experimentally by ingestion. It can cause disturbance of color vision. Objects first show bluish tinge, then yellow which is most prominent. Complete blindness may occur lasting perhaps for nearly a week. Dizziness, drowsiness, and nausea may also occur. Recovery is spontaneous. Combustible when exposed to heat or flame. When heated to decomposition it emits acrid smoke and irritating fumes.Safety information of Santonin (CAS NO.481-06-1):
Hazard Codes 
Xn
Risk Statements
22 Harmful if swallowed
Safety Statements
22 Do not breathe dust
24/25 Avoid contact with skin and eyes
RIDADR 2811
WGK Germany 3
RTECS LE3150000
HazardClass 6.1(a)
PackingGroup II
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unr-man LDLo:15 mg/kg
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85DCAI Poisoning; Toxicology, Symptoms, Treatments. 2 (1970),73. |
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orl-mus LD50:900 mg/kg
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NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),301. |
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ivn-mus LD50:180 mg/kg
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CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#02213 . |
